Results 51 to 60 of about 704,777 (227)

Kinetic and structural studies reveal a unique binding mode of sulfite to the nickel center in urease [PDF]

, 2016
Urease is the most efficient enzyme known to date, and catalyzes the hydrolysis of urea using two Ni(II) ions in the active site. Urease is a virulence factor in several human pathogens, while causing severe environmental and agronomic problems ...
Ciurli, Stefano, Mazzei, Luca, Cianci, Michele, Bertini, Leonardo, CIURLI, STEFANO LUCIANO, Musiani, Francesco, Benini, Stefano   +6 more
core   +1 more source

Sistema de microencapsulação de urease com quitosana - PVA : reatividade e aplicações [PDF]

, 1997
Tese (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas.Neste trabalho foi investigada a microencapsulação da urease na forma de extrato bruto (EE), através do método de coacervação salina, utilizando-se o ...
Miguez, Maria Jose Brandão
core  

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

N-Arylacetamide derivatives of methyl 1,2-benzothiazine-3-carboxylate as potential drug candidates for urease inhibition

Royal Society Open Science, 2023
Urease enzyme is an infectious factor that provokes the growth and colonization of virulence pathogenic bacteria in humans. To overcome the deleterious effects of bacterial infections, inhibition of urease enzyme is one of the promising approaches.
Sajila Hina, Sumera Zaib, Maliha Uroos, Muhammad Zia-ur-Rehman, Rubina Munir, Huma Riaz, Quratulain Syed, Syed Hussain Imam Abidi   +7 more
doaj   +1 more source

An inhibitor of urease activity effectively reduces ammonia emissions from soil treated with urea under Mediterranean conditions [PDF]

, 2008
7 páginas y 3 figurasUrea is an important source of ammonia (NH3) emissions to the atmosphere from agricultural soils. Abatement strategies are necessary in order to achieve NH3 emission targets by reducing those emissions.
Misselbrook, T., Arce, A., Mingot, J. I., Díez López, José Antonio, Sanz-Cobena, A., Arce, Augusto, Misselbrook, T. H., Diez, J. A., Sanz-Cobena, Alberto, Mingot, Juan I., Vallejo, Antonio, Vallejo, A., Misselbrook, Tom   +12 more
core   +1 more source

Inhibition of urease by some new synthesized 1,2,4-triazol derivatives: Inhibition mechanism and molecular docking [PDF]

, 2019
Urease is a metalloenzyme that catalyzes the hydrolysis of urea to ammonia and carbon dioxide. This ammonia secretion may cause significant increase in pH and is responsible for negative effects of urease activity in human health and agriculture.
ÇOLAK, AHMET, KALFA, Aylin, YAŞAR, AHMET, DEMIR, ELİF, BEKİRCAN, OLCAY   +4 more
core   +3 more sources

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Influence of inhibitor Limus on the microbiological activity of soils when growing barley with application of urea [PDF]

BIO Web of Conferences
This study assessed the impact of the urease inhibitor Limus on the microbiological properties of soil during barley cultivation. It examined the activity of microbial groups associated with the nitrogen cycle (ammonifiers, denitrifiers), urease enzyme ...
Kozlova Еkaterina, Korneykova Maria, Vasenev Viacheslav, Volkova Yulia, Sotnikova Yulia   +4 more
doaj   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source