Results 81 to 90 of about 704,777 (227)

Synergistic effect of inhibitors (allylthiourea and 1,2,4-triazole) on the activity of wheat soil urease to reduce nitrogen loss

Case Studies in Chemical and Environmental Engineering, 2020
Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea, forming CO2 and ammonia. Urease activity in soil enables several microorganisms to utilize urea as their nitrogen source.
Mahnoor Qayyum Khan, Khalil-ur Rahman, Usman Ghani, Aneela Basharat, Sarmad Ahmad Qamar, Muhammad Bilal   +5 more
doaj   +1 more source

N-monoarylacetothioureas as potent urease inhibitors: synthesis, SAR, and biological evaluation

, 2019
A urease inhibitor with good in vivo profile is considered as an alternative agent for treating infections caused by urease-producing bacteria such as Helicobacter pylori.
Jie-Ling He (8194506), Juan Yi (422472), Tian-Li Zhou (8194509), Shan-Shan Liu (1593079), Hai-Liang Zhu (439337), Zhu-Ping Xiao (1456651), Xing-Ming Pan (8194503), Wei-Yi Li (8194494), Wei-Wei Ni (2511025), Hai-Lian Fang (8194500), Ya-Xi Ye (8194497), Mi Zhou (9884)   +11 more
core   +1 more source

)‐one Moiety as Potential Urease Inhibitors

, 2022
Novel pyrazoline derivatives containing benzo[d]thiazol-2(3H)-one moiety were synthesized and screened for their inhibitory properties against urease, a clinically important metabolic enzyme.
Tatar, Gizem, Baltaş, Nimet, Nimet Baltaş, Gizem Tatar, Fatih Tok, Bedia Koçyiğit‐Kaymakçıoğlu, Koçyiğiy Kaymakçıoğlu, Bedia, TATAR YILMAZ, GİZEM, KAYMAKÇIOĞLU, BEDİA, TOK, FATİH   +9 more
core   +1 more source

Antimicrobial bilayer starch film containing zein electrospun fibers encapsulating thyme essential oil for cherry tomato packaging

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background This study evaluated the antimicrobial activity of thyme essential oil (TEO) encapsulated in electrospun zein fibers for use in bilayer films as active packaging for cherry tomatoes. The antimicrobial activity of TEO and bilayer films with 20%, 40%, and 60% TEO was assessed with agar diffusion and microatmosphere assays.
Jéssica Silveira Vitoria, Tamires Soares Schug, Laura Martins Fonseca, Débora A. Campos, Manuela Pintado, Tatiane Kuka Valente Gandra, Elessandra da Rosa Zavareze, Eliezer Avila Gandra   +7 more
wiley   +1 more source

Mechanism of Combined Improvement of Saline‐Alkali Soil by Artificial Humic Acid and Microbial Inoculant

Land Degradation &Development, EarlyView.
ABSTRACT To address the widespread constraints imposed by saline‐alkaline soils on agricultural production worldwide, the combined reclamation and carbon cycle regulation effects of artificial humic acid (AHA) and a multifunctional microbial inoculant were evaluated through pot experiments. Results demonstrated that co‐application of AHA (4 g·kg−1) and
Ying Zhao, Rui Zhang, Zeyu Zhang, Fan Yang, Zhuqing Liu   +4 more
wiley   +1 more source

Assessment of Some Aminoglycoside Drugs Repurposing as Helicobacter pylori Urease Enzyme Inhibitors by In silico and In vitro

Medical Journal of Babylon
Background: A Helicobacter pylori is a Gram negative bacterium associated with gastrointestinal tract disease. Helicobacter pylori can grow in extreme acidic condition like stomach under microaerobic conditions.
Tamadhur Mohammed Ali Abd Alhasan, Majid Kadhim Abbas, Mudher Khudhur Mohammed   +2 more
doaj   +1 more source

Microplastic‐Induced Shifts in Soil Leachate Chemistry, Redox Response, Biochemistry, and Biofilm Dynamics

Land Degradation &Development, EarlyView.
ABSTRACT Microplastics (MPs) are increasingly recognized as soil contaminants, yet their time‐dependent associations with dissolved organic matter characteristics, redox behavior, biochemical constituents, and biofilm‐associated responses are often investigated separately.
Asli Baysal, Hasan Saygin, Pinar Kayisoglu, Sinem Karniyarik   +3 more
wiley   +1 more source

Harnessing microbial-derived metabolites in the urinary tract to prevent infection induced catheter encrustation

Nature Communications
Proteus mirabilis is a predominant cause of catheter associated urinary tract infection (CAUTI), and a key virulence factor is its urease enzyme which can increase urine pH and form urinary stones, causing catheter blockage and facilitating bacteremia ...
L. Beryl Guterman, Madalyn Motsay, Benjamin C. Hunt, Aimee L. Brauer, Brian S. Learman, Mindula K. Wijayahena, Alexander C. Hoepker, Diana S. Aga, Brittany Francis, Beatriz M. Fontoura, George L. Donati, Peter J. Bush, Namrata Deka, Chelsie E. Armbruster   +13 more
doaj   +1 more source

Gramine Suppresses Myofibroblast Activation and ECM Accumulation in Renal Fibrosis by Targeting the NF‐κB/NLRP3 and TGF‐β1/Smad Pathways

Phytotherapy Research, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is driven by persistent inflammation and progressive fibrosis, leading to irreversible renal damage. Gramine (GMN), an indole alkaloid, has broad pharmacological benefits. However, its therapeutic potential against renal fibrosis remains unexplored.
Shobhit Gairola, Archana Bhatta, Tushar Mishra, Ravinder K. Kaundal   +3 more
wiley   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source