Results 71 to 80 of about 52,663 (318)

FIGO guideline on liver disease and pregnancy

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management.
Melanie Nana   +24 more
wiley   +1 more source

Posterior reversible encephalopathy syndrome in a patient with lupus nephritis

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2012
Posterior reversible encephalopathy syndrome (PRES) is characterized by acute onset of headache, nausea, focal neurological deficits or seizures along with radiological findings of white matter defects in the parietal and occipital lobes.
Huseyin Kadikoy   +5 more
doaj   +1 more source

Ulcer in a dialysis patient: Calciphylaxis or something simpler

open access: yesClinical Case Reports, 2022
Ulcers in dialysis patients have multiple etiologies; uremic pruritis is common in dialysis patients and is associated with poor outcomes; however, it is more likely to be underdiagnosed as we usually think about more serious etiologies as calciphylaxis.
Amr Mohamed, Salem Thabet
doaj   +1 more source

Linking preclinical models to clinical realities: VEGF/VEGFR inhibitors and thrombotic microangiopathy in cancer therapy

open access: yesiMetaOmics, EarlyView.
This study investigates the risk of thrombotic microangiopathy (TMA) induced by vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) inhibitors in cancer therapy. Using data from the FDA Adverse Event Reporting System (FAERS), the WHO Global Database for Adverse Drug Reactions (Vigibase), and The Cancer ...
Aimin Jiang   +7 more
wiley   +1 more source

Is uremia an example of acquired inhibition of receptor-mediated endocytosis? [PDF]

open access: yes, 1993
Many factors that inhibit receptor-mediated endocytosis (RME) at postreceptor level in vitro have been described: (i) high concentration of urea, (ii) lowering of intracellular pH, (iii) hypotonic or hypertonic media, (iv) intracellular potassium ...
Stantchev, Tzanko S.
core   +2 more sources

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Nurses and Physicians\' Viewpoint toward Interprofessional Collaboration

open access: yesنشریه پرستاری ایران, 2013
Background and Aim : Collaboration between nurses and physicians is essential for providing primary care and it is key factor for facilitating empowerment and rehabilitation of patients.
M Jasemi   +4 more
doaj  

Early history of uremia [PDF]

open access: yesKidney International, 1988
The important, but rather vague, observations of Boerhaave (1668—1738) [II in Holland and the more precise ones of Rouelle Ic Cadet (1718—1779) [21 in France suggested the presence of large quantities of an unknown "soapy" substance in the urine. Between 1797 and 1808, A. Fourcroy (1755—1809) and N.
openaire   +2 more sources

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez   +8 more
wiley   +1 more source

The Effect of Treatment of Acidosis on Calcium Balance in Patients with Chronic Azotemic Renal Disease [PDF]

open access: yes, 1967
Small but statistically significant negative calcium balances were found in each of eight studies in seven patients with chronic azotemic renal disease when stable metabolic acidosis was present.
Lemann, Jacob, Jr.   +2 more
core   +3 more sources

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