Results 61 to 70 of about 25,382 (196)

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

American Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 1953-1972, September 2026.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll, Yves Alembik, Marie‐Paule Roth   +2 more
wiley   +1 more source

3D MR Fingerprinting for Quantitative Bladder Wall T1, T2, and M0 Mapping in Healthy Subjects at 1.5 T and 3 T

NMR in Biomedicine, Volume 39, Issue 9, September 2026.
Current diagnostic tests for lower urinary tract symptoms lack the ability to assess tissue‐level alterations in the bladder wall. This study introduces an approach for simultaneous high‐resolution 3D T1, T2, and proton density mapping of the bladder wall using magnetic resonance fingerprinting combined with a self‐supervised deep learning ...
Shane A. Wells, Giulia M. Ippolito, Melis Ozkan, Wilson Sui, Anne P. Cameron, Jesse I. Hamilton   +5 more
wiley   +1 more source

APOPTOSIS IN IPSILATERAL KIDNEY. COMPARISON BETWEEN GROUP RECEIVING VERAPAMIL AND CONTROL GROUP POST-ARTIFICAL TOTAL UNILATERAL URETERAL OBSTRUCTION

Jurnal Urologi Indonesia, 2014
Objective: Obstruction of the urinary tract has marked effects on renal blood flow, glomerular filtration rate (GFR), and tubular function. Ureteral obstruction results in an injury response that can progress to irreversible renal fibrosis and tubular ...
Syakri Syahrir, Soetojo Soetojo, Adi Santoso, Endang Joewarini, Widodo J P   +4 more
doaj   +1 more source

Long‐term insights: Seven years of conservative management for deep endometriosis in the bowel

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1848-1859, September 2026.
Long‐term conservative management of bowel endometriosis can maintain stable symptoms and sustained quality of life. Those who need surgery tend to have more severe pain, larger nodules, and a lower quality of life. Abstract Introduction Deep endometriosis (DE) involving the bowel presents a complex management challenge.
Gitte Bro Schmidt, Ulrik Schiøler Kesmodel, Mikkel Seyer‐Hansen, Anne Gisselmann Egekvist   +3 more
wiley   +1 more source

Effects of the Surgical Ligation of the Ureter in Different Locations on the Kidney over Time in the Rat Model

Advances in Urology
Purpose. To evaluate the effects of the surgical ligation of the ureter in different locations on the kidney over time in the rat model. Methods. A total of 155 rats were enrolled and randomly divided into the case (n = 150) and control (n = 5) groups ...
Abdolreza Mohammadi, Leila Zareian Baghdadabad, Parisa Zahmatkesh, Hedieh Moradi Tabriz, Alireza Khajavi, Gholamreza Mesbah, Parsa Nikoofar, Seyed Mohammad Kazem Aghamir   +7 more
doaj   +1 more source

Interference of enalaprilat on glomerular permeability to macromolecules (IGG) in acute unilateral ureteral obstruction in rats

International Brazilian Journal of Urology, 2006
INTRODUCTION: Unilateral ureteral obstruction breaks out events that cause the transitory increase of glomerular permeability to macromolecules, both in the obstructed kidney and in the contralateral kidney, suggesting the presence of some factor, with a
Rene M. Oliveira, Antonio A. Oliveira Neto, Luiz C. Miranda   +2 more
doaj   +1 more source

Obstructive Pyelonephritis Secondary to Ureteral Compression by an Intra‐Abdominal Desmoid Tumor in Familial Adenomatous Polyposis: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT In patients with familial adenomatous polyposis, intra‐abdominal desmoid tumors should be recognized as a rare but important cause of ureteral obstruction and obstructive pyelonephritis. Prompt cross‐sectional imaging, early recognition, and multidisciplinary management are essential for preserving renal function, treating infection, and ...
Alireza Mehrban, Mehdi Karimi, Mohammad Taghi Hamidian, Mahdi Masoumi, Elahe Tari Najarkolaei, Abdolreza Babamahmoodi   +5 more
wiley   +1 more source

Establishment and observation of a new and ideal reversible model of PUUO

Renal Failure, 2017
Objective: We established a novel procedure to generate a reversible partial unilateral ureteral obstruction (PUUO) in rabbit. The method allows us to reliably measure the degree of ureteral obstruction in live animals, and thus could be a useful tool ...
Wei Zhu, Xi Zheng, Chunming Jiang, Haifeng Huang, Wei Wang, He Liu, Wei Jiang, Lin Yang, Shengjie Zhang, Miao Zhang, Dalong Zhu, Xiang Yan   +11 more
doaj   +1 more source

The metabolic‐immune hub: Dual roles of indoleamine 2,3‐dioxygenase in the acute kidney injury‐to‐chronic kidney disease transition and therapeutic perspectives

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
1. Indoleamine 2,3‐dioxygenase (IDO) acts as a time‐dependent metabolic–immune switch in the acute kidney injury‐to‐chronic kidney disease transition, protective early but pathogenic when sustained. 2. Early protection (regulatory T cell expansion, M2 polarisation and ferroptosis suppression) gives way to general control nonderepressible 2‐driven ...
Ziyi Qiu, Binbin Pan
wiley   +1 more source