Results 51 to 60 of about 26,220 (307)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Prise en Charge Péri-Opératoire des Urgences Chirurgicales Post-Traumatiques au Gabon

Health Research in Africa
RÉSUMÉ Introduction. Les urgences chirurgicales post-traumatiques sont fréquentes au trauma center d’Owendo. L’objectif de ce travail était de décrire la prise en charge péri-opératoire des urgences chirurgicales post-traumatiques au Centre Hospitalier ...
Matsanga Arthur, Sagbo Ada Lesly Vanessa, Ifoudji Makao A, Okoué Ondo R, Ekegue N, Mpiga Mickoto B, Obame R   +6 more
doaj   +1 more source

Péritonite primitive: entité réelle mais de diagnostic difficile

The Pan African Medical Journal, 2012
Les péritonites primitives sont rares chez des patients sans facteurs de risques. Elles simulent les péritonites secondaires. C’est pourquoi leur diagnostic ne peut être que peropératoire. Nous rapportons deux cas de péritonites primitives dans le but de
Rajae Yamoul, Mohammed Najih, Mohamed Absi, Mohamed Ouanani, Mahjoub Echerrab, Hassan EL Alami, Mohamed Amraoui, Abdelkader Errougani, Mohamed Rachid Chkoff   +8 more
doaj   +1 more source

Acute fissuration of a giant splenic artery aneurysm detected by point-of-care ultrasound: case report

Critical Ultrasound Journal, 2018
Background Epigastric pain is frequent in Emergency Medicine and remains a challenging situation. Besides benign etiologies such as gastritis or uncomplicated cholelithiasis, it could reveal myocardial infarction or vascular disease.
Philippe Le Conte, David Trewick, Philippe Pes, Eric Frampas, Eric Batard, Winfocus-France Group   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Corps étranger intra-rectal: médecine traditionnelle ou trouble de comportement?

The Pan African Medical Journal, 2014
L'insertion de corps étranger (CE) par l'anus est devenue un motif assez fréquent de consultation aux urgences. Cette introduction du CE est rarement accidentelle et se voit surtout dans le cadre d'actes sexuels et/ou parfois criminels survenant sur un ...
Pierlesky Elion Ossibi, Khalid Mazaz
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Le rôle de l'infirmière à l'accueil des urgences pour la prise en charge de la douleur aiguë: revue de la littérature [PDF]

, 2017
La douleur est l’un des principaux motifs de consultation auprès des services d’urgences. Cependant, l’oligo-analgésie reste très présente et les patients ne sont pas satisfaits de la prise en charge de ce symptôme.
Nowak, Frédérique, Schmid, Alice,
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Decompressive craniotomy in the management of malignant cerebral venous thrombo- sis: A case report

Journal de la Faculté de Médecine d'Oran, 2022
Introduction - Cerebral venous thrombosis is a condition that usually affects young woman. It exposes to intracranial hypertension, which in rare cases entails a commitment that compromises the vital prognosis.
Soumia Benbernou, Abdelmoumene Ryad Ayoun, Houria Mokhtari Djebli, Maamer Bouchakour, Batoul Chalabi, Nabil Ghomari, Khalida Bouyacoub, Abdelkader Azza, Malik Sofiane Iles, Manel Aich   +9 more
doaj