Results 71 to 80 of about 4,915 (262)

Les invaginations intestinales chez l'adulte: à propos de 17 cas

The Pan African Medical Journal, 2012
L'invagination intestinale est une affection rare chez l'adulte Elle conduit le plus souvent à la découverte d'une cause organique pouvant être tumorale Le but de notre travail est de dégager les particularités épidémiologiques diagnostiques et ...
Elhattabi Khalid, Bensardi Fatimazahra, Khaiz Driss, Fadil Abdelaziz, Raouah Abdellatif, Lefriyekh Rachid1, Benissa Nadia, Berrada Saad, Zerouali Ouariti Najib   +8 more
doaj   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Profil de consommation des médicaments au service des urgences de l’Institut de Cardiologie d’Abidjan – Côte d’ivoire

Journal Africain de Technologie Pharmaceutique et Biopharmacie
La disponibilité des médicaments pour les urgences cardiovasculaires permet une prise en charge adéquate des patients. Cette étude avait pour objectif d’évaluer le profil de consommation des médicaments au service des urgences de l’Institut de ...
Gbongue Eric Tia, Kouakou Etienne Effo, Gniènèfèrètien Nounaféri Awa SILUE , Konan Hamed KOUAKOU , Ahou Axelle Edith KOUADIO , Moulad Ephraïm ALLIMAN , Amankou Donaldo Jean-Fabius AHUA , Geneviève N’GUESSAN-IRIE , N’doua Gisèle KOUAKOU-SIRANSY   +8 more
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Total rupture of hydatid cyst of liver in to common bile duct: a case report

The Pan African Medical Journal, 2014
Rupture of hydatid liver cyst into biliary tree is frequent complications that involvethe common hepatic duct, lobar biliary branches, the small intrahepatic bile ducts,but rarely rupture into common bile duct. The rupture of hydatid cyst is serious life
Hassan Robleh, Fahmi Yassine, Khaiz Driss, Elhattabi Khalid, Bensardi Fatima-zahra, Berrada Saad, Lefriyekh Rachid, Fadil Abdalaziz, Zerouali Ouariti Najib   +8 more
doaj   +1 more source

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Lipome intramédullaire: à propos d'une observation

The Pan African Medical Journal, 2018
Les lipomes intramédullaires sont des lésions bénignes rares qui représentent environ 1% de l'ensemble des tumeurs de la moelle épinière. Nous rapportons un nouveau cas de lipome intramédullaire non dysraphique confirmé histologiquement.
Soukaina Wakrim, Najwa Touil, Ousmane Traore, Omar Kacimi, Nabil Chikhaoui   +4 more
doaj   +1 more source

Founding Editorial: Neuro‐Drug Discovery

Neuro-Drug Discovery, EarlyView.
Wenbin Li
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source