Results 51 to 60 of about 14,438 (295)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Les urgences du moment

open access: yes, 1987
Dietz François. Les urgences du moment. In: Autres Temps. Les cahiers du christianisme social. N°13, 1987. pp.
Dietz, François
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Péritonite primitive: entité réelle mais de diagnostic difficile

open access: yesThe Pan African Medical Journal, 2012
Les péritonites primitives sont rares chez des patients sans facteurs de risques. Elles simulent les péritonites secondaires. C’est pourquoi leur diagnostic ne peut être que peropératoire. Nous rapportons deux cas de péritonites primitives dans le but de
Rajae Yamoul   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Bien débuter. Urgences

open access: yes, 2022
IDE = Infirmier(ière) diplômé(e) d'État. - La couv. porte aussi : " "Rôle de l'IDE" ; "Prérequis" ; "Situations cliniques prévalentes" ; "Boîte à outils".
Kerever, Sébastien   +2 more
core   +1 more source

Paragangliome retropéritonéal: à propos d'un cas et revue de littérature

open access: yesThe Pan African Medical Journal, 2015
Les paragangliomes rétropéritonéaux non fonctionnels sont des tumeurs rares. Ils sont définis comme des tumeurs chromaffines extra- surrénaliennes et représentent environ 1/5ème des tumeurs chromaffines.
Yassine Fahmi   +8 more
doaj   +1 more source

Particularités de la prise en charge des patients douloureux chronique aux urgences

open access: yes, 2022
À peu près 30 % des patients admis aux urgences ont une douloureux chronique (DC). Parmi ceux-ci, 20 à 30 % ont pour motif d’admission une douleur en rapport avec leur douleur habituelle, soit 10 % des patients des urgences. L’objectif du présent article
LVOVSCHI, Virginie   +4 more
core   +1 more source

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