Results 61 to 70 of about 14,438 (295)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Prise en Charge Péri-Opératoire des Urgences Chirurgicales Post-Traumatiques au Gabon
Health Research in AfricaRÉSUMÉ Introduction. Les urgences chirurgicales post-traumatiques sont fréquentes au trauma center d’Owendo. L’objectif de ce travail était de décrire la prise en charge péri-opératoire des urgences chirurgicales post-traumatiques au Centre Hospitalier ...
Matsanga Arthur +6 more
doaj +1 more source
Urgence climatique, urgence sociale
Calenda, 2022 Pour son numéro du dernier trimestre 2022, la revue s’attachera à interroger la manière dont le travail social peut s’inscrire dans les logiques de développement durable, i.e. une conception du développement qui intègre, sur le long terme, des objectifs écologiques et sociaux aux objectifs strictement économiques.
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Corps étranger intra-rectal: médecine traditionnelle ou trouble de comportement?
The Pan African Medical Journal, 2014 L'insertion de corps étranger (CE) par l'anus est devenue un motif assez fréquent de consultation aux urgences. Cette introduction du CE est rarement accidentelle et se voit surtout dans le cadre d'actes sexuels et/ou parfois criminels survenant sur un ...
Pierlesky Elion Ossibi, Khalid Mazaz
doaj +1 more source
Critical Ultrasound Journal, 2018 Background Epigastric pain is frequent in Emergency Medicine and remains a challenging situation. Besides benign etiologies such as gastritis or uncomplicated cholelithiasis, it could reveal myocardial infarction or vascular disease.
Philippe Le Conte +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Douleur thoracique aux urgences : utilisation adéquate des scores diagnostiques
, 2020 Résumé La douleur thoracique est un motif très fréquent de consultation aux urgences. Le diagnostic différentiel est large et regroupe diverses étiologies parmi lesquelles les syndromes coronariens aigus (SCA) qui sont à l’avantplan. L’exclusion d’un SCA
Moumneh, Thomas +3 more
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Decompressive craniotomy in the management of malignant cerebral venous thrombo- sis: A case report
Journal de la Faculté de Médecine d'Oran, 2022 Introduction - Cerebral venous thrombosis is a condition that usually affects young woman. It exposes to intracranial hypertension, which in rare cases entails a commitment that compromises the vital prognosis.
Soumia Benbernou +9 more
doaj