Results 11 to 20 of about 123,390 (261)

Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System

open access: yesCells, 2022
Background: Hyperuricemia is a common laboratory finding in pregnant women compromised by preeclampsia. A growing body of evidence suggests that uric acid is involved in the pathogenesis of preeclampsia.
Benjamin P. Lüscher   +4 more
doaj   +1 more source

Serum uric acid level predicts the progression of amyotrophic lateral sclerosis following treatment with edaravone

open access: yesRedox Report, 2022
Introduction Uric acid and edaravone might exert a neuroprotective effect in amyotrophic lateral sclerosis (ALS) by reducing oxidative stress. We analyzed whether the treatment effect of edaravone is pronounced in patients whose uric acid level increased
Hee Jo Han   +4 more
doaj   +1 more source

Are Uric Acid Level and Uric Acid/Creatinine Ratio Reliable Biomarkers for Idiopathic Parkinson’s Disease Severity?

open access: yesHaseki Tıp Bülteni, 2020
Aim:It has been proposed that elevated levels of uric acid (UA) has a protective effect against the development of Idiopathic Parkinson’s Disease (IPD), however, since IPD has been found to be more common in gout patients, their relationship became ...
Vasfiye Burcu Albay, Mesude Tütüncü
doaj   +1 more source

Correlation of Serum Uric Acid and Serum Uric Acid/Creatinine Ratio Levels with Adverse Pregnancy Outcomes in Late Pregnancy [PDF]

open access: yesZhongguo quanke yixue
Background The disorder of serum uric acid metabolism during pregnancy is associated with adverse pregnancy outcomes, while few studies have analyzed and compared the correlation of serum uric acid and serum uric acid/creatinine ratio levels with adverse
ZHAO Ru, HAN Chen, HUANG Zeyu, WANG Qian, HU Jun, GE Zhijuan, BI Yan, SHEN Shanmei
doaj   +1 more source

Hyperuricemia causes pancreatic β-cell death and dysfunction through NF-κB signaling pathway. [PDF]

open access: yesPLoS ONE, 2013
Accumulating clinical evidence suggests that hyperuricemia is associated with an increased risk of type 2 diabetes. However, it is still unclear whether elevated levels of uric acid can cause direct injury of pancreatic β-cells.
Lu Jia   +11 more
doaj   +1 more source

Elevated Uric Acid Levels with Early Chronic Kidney Disease as an Indicator of New-Onset Ischemic Heart Disease: A Cohort of Koreans without Diabetes

open access: yesBiomedicines, 2023
Several studies have showed that hyperuricemia is related to the development of ischemic heart disease (IHD). There is also growing evidence indicating that hyperuricemia may contribute to the progression of IHD as a pathogenic factor.
Sung-Bum Lee   +4 more
doaj   +1 more source

Uric acid and evolution [PDF]

open access: yesRheumatology, 2010
Uric acid (UA) is the end product of purine metabolism in humans due to the loss of uricase activity by various mutations of its gene during the Miocene epoch, which led to humans having higher UA levels than other mammals. Furthermore, 90% of UA filtered by the kidneys is reabsorbed, instead of being excreted.
Bonifacio, Álvarez-Lario   +1 more
openaire   +2 more sources

Optical monitoring of hemodialysis using noninvasive measurement of uric acid in the dialysate

open access: yesScientific Reports, 2023
The aim of this study was to present a methodology for predicting changes in uric acid concentrations in the blood of chronically hemodialyzed patients based on an optical measurement of the intensity of selected wavelengths in the dialysate.
Wojciech Żyłka   +8 more
doaj   +1 more source

The Role of the Intestine in the Development of Hyperuricemia

open access: yesFrontiers in Immunology, 2022
Gout is a common inflammatory arthritis caused by the deposition of sodium urate crystals in the joints. Hyperuricemia is the fundamental factor of gout.
Hui Yin   +5 more
doaj   +1 more source

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