Results 211 to 220 of about 229,255 (286)

Seizures and electroencephalographic findings in inborn errors of metabolism: Clues to differential diagnosis in the neonatal period, infancy, childhood and adolescence, and review of the literature

open access: yesEpileptic Disorders, EarlyView.
Abstract Although inborn errors of metabolism (IEM) are a rare cause of epilepsy, seizures are a common presentation in these disorders. Seizures in IEM are frequently refractory to conventional anti‐seizure medication and might warrant initiation of specific treatments based on vitamins or dietary modifications or provision of alternative substrates ...
D. Kapoor   +7 more
wiley   +1 more source

Physiological serum uric acid concentrations correlate with arterial stiffness in a sex-dependent manner. [PDF]

open access: yesBMC Med
Thews O   +29 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Enhanced Blood‐Brain Barrier Penetrability of BACE1 SiRNA‐Loaded Prussian Blue Nanocomplexes for Alzheimer's Disease Synergy Therapy

open access: yesExploration, EarlyView.
BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding   +9 more
wiley   +1 more source

Higher uric acid associated with elevated IL‑6 and IL‑1β levels in older inpatients: a cross‑sectional study. [PDF]

open access: yesRheumatol Int
Husejko J   +9 more
europepmc   +1 more source

Uric Acid‐Lowering and Anti‐Hyperuricemia Effects of Plant‐Based Nutraceuticals and Foods: A Review

open access: yesFood Chemistry International, EarlyView.
Increased UA production and/or decreased UA secretion cause hyperuricemia. Effects and mechanism of flavonoids in reducing UA are summarized. Terpenoids, saponins, alkaloids, vitamin C, polysaccharides, peptides are effective. Plant‐based foods with UA‐lowering ability are reviewed.
Linwei He, Wenjian Yang, Jianhui Liu
wiley   +1 more source

Goat Milk‐Derived Extracellular Vesicles Attenuate Hydrogen Peroxide‐Treated Cell Damage in Human Skin Fibroblasts

open access: yesFood Frontiers, EarlyView.
2 types of goat milk extracellular vesicles (GMEVs‐1 and GMEVs‐2) were investigated for their migration and skin permeation abilities in vitro and in vivo. Using an H2O2‐induced model in human skin fibroblasts cells, we demonstrated their protective effects of against oxidative stress, highlighting their potential for skin health applications ...
Chunping Chen   +8 more
wiley   +1 more source

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