Results 51 to 60 of about 126,447 (164)

The Relationship of Protein Diet with Uric Acid Levels in the Elderly in Outpatient Polyclinics : A Cross-sectional Study

Lentera Perawat
Uric acid is a common metabolic disorder among the elderly, often associated with dietary patterns, especially high-purine protein intake. Improper dietary management can worsen uric acid levels and increase the risk of chronic complications.
Meydiana Putri Pratiwi, Andre Utama Saputra, Serli Wulan Safitri, Selamat Parmin   +3 more
doaj   +1 more source

ON THE SYNTHESIS OF URIC ACID. [PDF]

The Lancet, 1886
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openaire   +2 more sources

Uric acid, an important screening tool to detect inborn errors of metabolism: a case series

BMC Research Notes, 2017
Background Uric acid is the metabolic end product of purine metabolism in humans. Altered serum and urine uric acid level (both above and below the reference ranges) is an indispensable marker in detecting rare inborn errors of metabolism.
Eresha Jasinge, Grace Angeline Malarnangai Kularatnam, Hewa Warawitage Dilanthi, Dinesha Maduri Vidanapathirana, Kandana Liyanage Subhashinie Priyadarshika Kapilani Menike Jayasena, Nambage Dona Priyani Dhammika Chandrasiri, Neluwa Liyanage Ruwan Indika, Pyara Dilani Ratnayake, Vindya Nandani Gunasekara, Lynette Dianne Fairbanks, Blanka Stiburkova   +10 more
doaj   +1 more source

Concentration-Dependent Inhibitory Effect of Irbesartan on Renal Uric Acid Transporters

Journal of Pharmacological Sciences, 2010
Hyperuricemia is currently recognized as a risk factor for cardiovascular diseases. It has been reported that the angiotensin II–receptor blocker (ARB) losartan decreases serum uric acid level.
Makiko Nakamura, Naohiko Anzai, Promsuk Jutabha, Hiroyuki Sato, Hiroyuki Sakurai, Kimiyoshi Ichida   +5 more
doaj   +1 more source

Effects of Marine Fish Oligopeptide Composite Preparation on Reducing Uric Acid and Repairing Kidney Damage

Shipin gongye ke-ji
Objective: To investigate the effects of marine fish oligopeptide composite preparation (MFOCP) on reducing uric acid and repairing kidney damage and the underlying mechanisms.
Zijia LU, Yu GAO, Yao XIE, Fengqin FENG
doaj   +1 more source

Uric acid disrupts hypochlorous acid production and the bactericidal activity of HL-60 cells

Redox Biology, 2018
Uric acid is the end product of purine metabolism in humans and is an alternative physiological substrate for myeloperoxidase. Oxidation of uric acid by this enzyme generates uric acid free radical and urate hydroperoxide, a strong oxidant and ...
Larissa A.C. Carvalho, João P.P.B. Lopes, Gilberto H. Kaihami, Railmara P. Silva, Alexandre Bruni-Cardoso, Regina L. Baldini, Flavia C. Meotti   +6 more
doaj   +1 more source

The Development of Reproducible and Selective Uric Acid Biosensor by Using Electrodeposited Polytyramine as Matrix Polymer

Indonesian Journal of Chemistry, 2017
A versatile method for the construction of reproducible and high selective uric acid biosensor is explained. Electrodeposited polytyramine is used as biosensor matrixes due to its compatibility to immobilize enzyme uric oxidase in the membrane electrode.
Manihar Situmorang, Isnaini Nurwahyuni
doaj   +1 more source

Uric Acid and Oxidative Stress

Current Pharmaceutical Design, 2005
Uric acid is the final product of purine metabolism in humans. The final two reactions of its production catalyzing the conversion of hypoxanthine to xanthine and the latter to uric acid are catalysed by the enzyme xanthine oxidoreductase, which may attain two inter-convertible forms, namely xanthine dehydrogenase or xanthine oxidase.
Glantzounis, G. K., Tsimoyiannis, E. C., Kappas, A. M., Galaris, D. A.   +3 more
openaire   +3 more sources

Effects of allopurinol and febuxostat on uric acid transport and transporter expression in human umbilical vein endothelial cells.

PLoS ONE
Uric acid induces radical oxygen species formation, endothelial inflammation, and endothelial dysfunction which contributes to the progression of atherosclerosis.
Karel H van der Pol, Jan Koenderink, Jeroen J M W van den Heuvel, Petra van den Broek, Janny Peters, Imke D W van Bunningen, Jeanne Pertijs, Frans G M Russel, Jim Koldenhof, Wim J Morshuis, Joris van Drongelen, Tom J J Schirris, Andries van der Meer, Gerard A Rongen   +13 more
doaj   +1 more source

The Relationship of Acute Exacerbation Severity with Uric Acid and Uric Acid to Creatinine Ratio in Patients with Chronic Obstructive Pulmonary Disease

Haseki Tıp Bülteni, 2013
Aim: Acute exacerbation in chronic obstructive pulmonary disease (COPD) may result in a lot of systemic consequences due to hypoxemia and systemic inflammation.
Sinem Özbay Özyılmaz, İsa Özyılmaz, Osman Akın Serdar, Esra Uzaslan   +3 more
doaj   +1 more source