Results 61 to 70 of about 126,447 (164)

Reaction of Uric Acid with Peroxynitrite and Implications for the Mechanism of Neuroprotection by Uric Acid

open access: yesArchives of Biochemistry and Biophysics, 2000
Peroxynitrite, a biological oxidant formed from the reaction of nitric oxide with the superoxide radical, is associated with many pathologies, including neurodegenerative diseases, such as multiple sclerosis (MS). Gout (hyperuricemic) and MS are almost mutually exclusive, and uric acid has therapeutic effects in mice with experimental allergic ...
Squadrito, GL   +6 more
openaire   +3 more sources

Elevated serum uric acid before 20 weeks of gestation increases the risk of preeclampsia

open access: yesScientific Reports
This study aimed to investigate the association between serum uric acid level before gestational age of 20 weeks and preeclampsia. This study included pregnant women of three hospitals from January 2018 to June 2024.
Chenyang Zhao   +7 more
doaj   +1 more source

Correlation between serum levels of uric acid with bone turnover markers in postmenopausal women

open access: yesIranian South Medical Journal, 2015
Background: There is accumulation evidence regarding the protective role of higher serum uric acid in bone loss and osteoprotic fractures. This effect may arise from its antioxidant properties.
Fariba Karimi   +8 more
doaj  

Association between serum uric acid and the risk of breast cancer: A meta-analysis of observational studies

open access: yesThe International Journal of Biological Markers
Background The relationship between serum uric acid and breast cancer remains uncertain. This meta-analysis aimed to elucidate the dose-response association between elevated serum uric acid levels and breast cancer risk.
Liping Yang   +5 more
doaj   +1 more source

The effect of hyperuricemia on markers of endothelial dysfunction in patients with gout

open access: yesКлинический разбор в общей медицине
Uric acid is the end product of purine metabolism in humans. The concentration of uric acid can depend on many factors, for example: diet, alcohol consumption, gender, age, and concomitant pathologies. The level of uric acid is maintained at a level that
Konstantin V. Bubley   +3 more
doaj   +1 more source

Nephropathogenic infectious bronchitis virus induces epithelial-mesenchymal transition of renal tubular epithelial cells through the TGF-β/p-P38 pathway causing uric acid excretion disorder in chickens

open access: yesJournal of Virology
Nephropathogenic infectious bronchitis virus (NIBV) infection usually causes kidney enlargement and urate deposition in chickens, leading to sudden death.
Yunfeng Chen   +9 more
doaj   +1 more source

Serum uric acid concentration in acute pancreatitis is significantly higher than healthy population

open access: yesScientific Reports
Acute pancreatitis (AP) is a common disease caused by a variety of causes. Is uric acid associated with the onset of AP? The objective of this study was to assess whether uric acid concentration in AP patients was higher than that in healthy population ...
Linzhen Li, Han Wu, Hui Yin, Huiru Cao
doaj   +1 more source

Regulating uric acid

open access: yeseLife
Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum , are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.
openaire   +3 more sources

Uric acid and hypertension [PDF]

open access: yesHypertension Research, 2020
Miguel A, Lanaspa   +2 more
openaire   +2 more sources

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