Results 261 to 270 of about 99,858 (332)

Rapid Activation-Inactivation of Liver Uridine Diphosphate Glucose-Glycogen Transferase and Phosphorylase by Insulin and Glucagon in Vivo

, 1967
Jonathan S. Bishop, Joseph Larner
openalex   +1 more source

Impact of Model‐Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost

Clinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 378-385, August 2025.
Model‐informed drug development (MIDD) integrates data to quantify benefit/risk informing objective drug discovery and development decisions. An additional critical benefit of MIDD is postulated to be improvement in trial and program efficiencies. While the application of MIDD has grown, there have been no clear examples across programs to demonstrate ...
Vaishali Sahasrabudhe, Timothy Nicholas, Gianluca Nucci, Cynthia J Musante, Brian Corrigan   +4 more
wiley   +1 more source

Erianin inhibits the proliferation of lung cancer cells by suppressing mTOR activation and disrupting pyrimidine metabolism. [PDF]

Cancer Biol Med
Yan L, Liu Y, Huang Y, Sun X, Jiang H, Gu J, Xia J, Sun X, Sui X.   +8 more
europepmc   +1 more source

Modeling, virtual screening, and enzymatic docking of trehalose 6‐phosphate phosphatase and evaluation of the insecticidal effect of phthalimide, N‐(p‐tolylsulfonyl) on Aedes aegypti (Diptera: Culicidae)

Pest Management Science, Volume 81, Issue 8, Page 4777-4787, August 2025.
Schematic diagram of the experimental procedures used to perform the bioinformatic steps and insecticidal assays using trehalose 6‐phosphate phosphatase of Aedes aegypti and the molecule phthalimide, N‐(p‐tolylsulfonyl). Abstract BACKGROUND Aedes aegypti Linnaeus is a medically important vector because of its role in transmitting several arboviruses ...
Raquel Jemima Viana Lima, Fernando Berton Zanchi, Railton Marques de Souza Guimarães, Alexandre de Almeida e Silva   +3 more
wiley   +1 more source

Chemical reactivity of RNA and its modifications with hydrazine. [PDF]

Commun Chem
Yeşiltaç-Tosun N, Qi Y, Li C, Stafflinger H, Hollnagel K, Rusling L, Wöhnert J, Kaiser S, Kaiser S.   +8 more
europepmc   +1 more source

Effects of Insulin, Glucagon, and Glucocorticoids upon Hepatic Glycogen Synthesis from Uridine Diphosphate Glucose

, 1961
Donald F. Steiner, Vija Rauda, Robert H. Williams   +2 more
openalex   +1 more source

THE RING STRUCTURE OF URIDINE

Journal of Biological Chemistry, 1933
R. Stuart Tipson, P.A. Levene
openaire   +2 more sources

HSP104 and HSP20‐L Are Required by Aspergillus nidulans in Response to Attack by Fungivorous Springtail Sinella curviseta

Environmental Microbiology Reports, Volume 17, Issue 4, August 2025.
The heat shock proteins HSP104 and HSP20‐L of A. nidulans exhibit a reciprocal regulatory relationship to maintain physiological homeostasis in response to S. curviseta‐induced stress. ABSTRACT Heat shock proteins (HSPs) are conserved biomolecules that are consistently expressed and upregulated in response to stress.
Xiaomeng Wang, Juan Xi, Pengxu Chen, Yingying Chen, Keyu Chen, Weifa Zheng, Yanxia Zhao   +6 more
wiley   +1 more source

Entabolons: How Metabolites Modify the Biochemical Function of Proteins and Cause the Correlated Behavior of Proteins in Pathways. [PDF]

J Chem Inf Model
Skolnick J, Srinivasan B, Skolnick S, Edelman B, Zhou H.   +4 more
europepmc   +1 more source

Enzymatic Synthesis of the Peptide in a Uridine Nucleotide from Staphylococcus aureus

, 1960
Eiji Ito, Jack L. Strominger
openalex   +1 more source