Results 51 to 60 of about 4,673 (179)
Structure, mechanism and engineering of plant natural product glycosyltransferases
, 2009 Glycosylation is a key mechanism in determining chemical complexity and diversity of plant natural products, and influencing their chemical properties and bioactivities.
Wang, Xiaoqiang
core +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
Mass Spectrometry Reviews, Volume 45, Issue 4, Page 800-828, July/August 2026.ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
, 2016 Historical Background Extracellular purine and pyrimidine nucleotides act as signaling molecules through the activation of P2X ion channels and P2Y G protein-coupled receptors (GPCRs) (Abbracchio et al. 2006). Among the eight members of the P2Y receptor
Jacobson K A +3 more
core +1 more source
, 2022 Here, we present a two-step continuous flow enzymatic synthesis process in monolithic microreactors using basic sugars as substrates. In the first step UDP-glucose pyrophosphorylase (TaGalU) catalyses the synthesis of uridine-diphosphate-glucose (UDP-Glc)
Szymańska, Katarzyna (author) +8 more
core +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Quantitative analysis of the pyrimidine metabolism in pheochromocytoma PC-12 cells
, 1995 A detailed quantitative study of pyrimidine metabolism in exponentially growing rat pheochromocytoma PC-12 cells has been performed. The sizes of ribonucleotide pools have been analysed and the pathways and the rates of metabolism of uridine, cytidine ...
van Kuilenburg, A. B. +4 more
core +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
Advanced Science, Volume 13, Issue 36, 29 June 2026.An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
, 1996 The present study investigates the biotransformation of glucose with undine monophosphate (UMP) to obtain sugar nucleotide, UDP-glucose (UDPG), by the dried cells of Candida saitoana KCTC7249.
Dae Sil Lee +4 more
core +1 more source
Oxovanadium(IV) binding to ligands containing donor sites of biological relevance
, 2001 The (VO)-O-IV complex formation by a number of sugar ligands and their phosphate derivatives has been studied by the combined application of pH-potentiometric and spectroscopic (EPR and electronic absorption) techniques.
GARRIBBA, Eugenio +3 more
core +1 more source
Metabolic Fingerprinting of Urine Reveals Metabolite Changes in Women With Breast Cancer
Cancer Medicine, Volume 15, Issue 6, June 2026.This study uses metabolomics to compare urine, plasma and serum metabolite profiles across breast cancer, benign breast disease, symptomatic and healthy controls. Significant metabolic differences—especially in amino acids—were found between BC and other groups, with moderate correlations across biofluids, suggesting potential for non‐invasive BC ...
Nur Aimi Aliah Zainurin +9 more
wiley +1 more source