Results 31 to 40 of about 9,353 (186)

Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone [PDF]

, 2013
The main objectives of this work were to characterise a range of purified recombinant sterol 3β-glucosyltransferases and show that rational sampling of the diversity that exists within sterol 3β-glucosyltransferase sequence space can result in a range of
Altschul, Anthony Flinn, Bellu, Bonsor, Cantarel, Coutinho, Doerks, Gary W. Black, Grille, Hansen, Hashimoto, Julian S. Northen, Justin J. Perry, Laemmli, Lemmon, Li, Lynn G. Dover, Madina, Madina, Meng Zhang, O'Reilly, Oku, Palcic, Poppenberger, Rabbani, Robertson, Vatsala Malik, Warnecke, Weijers, Yang, Zea   +30 more
core   +1 more source

The role of Alg13 N-acetylglucosaminyl transferase in the expression of pathogenic features of Candida albicans. [PDF]

, 2017
Background: The pathogenic potential of Candida albicans depends on adhesion to the host cells mediated by highly glycosylated adhesins, hyphae formation and growth of biofilm. These factors require effective N-glycosylation of proteins.
Janik, Anna, Kruszewska, Joanna S., Niewiadomska, Monika, Palamarczyk, Grazyna, Perlinska-Lenart, Urszula, Piłsyk, Sebastian   +5 more
core   +1 more source

Characterization of galactose-dependent promoters from an oleaginous fungus Mortierella alpina 1S-4. [PDF]

, 2014
An inducible promoter is a useful tool for the controlled expression of a given gene. In this report, we describe galactose-dependent promoters for potential use in an oleaginous fungus Mortierella alpina.
Ando, Akinori, Kamada, Nozomu, Kikukawa, Hiroshi, Ochiai, Misa, Ogawa, Jun, Okuda, Tomoyo, Sakuradani, Eiji, Shima, Jun   +7 more
core   +1 more source

Metabolic processes sustaining the reviviscence of lichen Xanthoria elegans (Link) in high mountain environments. [PDF]

, 2007
International audienceTo survive in high mountain environments lichens must adapt themselves to alternating periods of desiccation and hydration. Respiration and photosynthesis of the foliaceous lichen, Xanthoria elegans, in the dehydrated state were ...
Aubert, Serge, Bligny, Richard, Boisson, Anne-Marie, Gout, Elisabeth, Juge, Christine   +4 more
core   +3 more sources

Thiamethoxam Resistance in Aphis gossypii Glover Relies on Multiple UDP-Glucuronosyltransferases

Frontiers in Physiology, 2018
Uridine diphosphate (UDP)-glycosyltransferases (UGTs) are major phase II enzymes that conjugate a variety of small lipophilic molecules with UDP sugars and alter them into more water-soluble metabolites. Therefore, glucosidation plays a major role in the
Yiou Pan, Fayi Tian, Xiang Wei, Yongqiang Wu, Xiwu Gao, Jinghui Xi, Qingli Shang   +6 more
doaj   +1 more source

Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs [PDF]

, 2019
O-Linked α-N-acetylgalactosamine (O-GalNAc) glycans constitute a major part of the human glycome. They are difficult to study because of the complex interplay of 20 distinct glycosyltransferase isoenzymes that initiate this form of glycosylation, the ...
Bertozzi, Carolyn R., Choi, Junwon, Debets, Marjoke F., Gehring, Jase, Gray, Melissa A., Malaker, Stacy A., Schumann, Benjamin, Takashima, Megumi, Timmermans, Suzanne B. P. E., Wagner, Lauren J. S.   +9 more
core   +3 more sources

Increased sugar content impairs pollen fertility and reduces seed-setting in high-photosynthetic-efficiency rice

Crop Journal
Crop yield depends on biomass, which is primarily associated with photosynthesis. We previously demonstrated that two photorespiratory bypasses, i.e., GOC (glycolate oxidase + oxalate oxidase + catalase) and GCGT (glycolate oxidase + catalase ...
Bodi Li, Anyao Huang, Limin Wang, Shuofan Wu, Zheng Xu, Xiaoyuan Chen, Zhisheng Zhang, Xinxiang Peng   +7 more
doaj   +1 more source

Substrate specificity provides insights into the sugar donor recognition mechanism of O-GlcNAc transferase (OGT). [PDF]

, 2013
O-Linked β-N-acetylglucosaminyl transferase (OGT) plays an important role in the glycosylation of proteins, which is involved in various cellular events.
Chen, Xi, Chen, Yi, Li, Lei, Liu, Pi, Liu, Xiaoyan, Ma, Xiaofeng, Muthana, Musleh M, Sun, Hong, Wang, Peng G, Yan, Hui, Zhang, Lianwen, Zhou, Feng   +11 more
core   +2 more sources

Molecular characterization of UGT94F2 and UGT86C4, two glycosyltransferases from Picrorhiza kurrooa: comparative structural insight and evaluation of substrate recognition.

PLoS ONE, 2013
Uridine diphosphate glycosyltransferases (UGTs) are pivotal in the process of glycosylation for decorating natural products with sugars. It is one of the versatile mechanisms in determining chemical complexity and diversity for the production of suite of
Wajid Waheed Bhat, Niha Dhar, Sumeer Razdan, Satiander Rana, Rukmankesh Mehra, Amit Nargotra, Rekha S Dhar, Nasheeman Ashraf, Ram Vishwakarma, Surrinder K Lattoo   +9 more
doaj   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source