Results 91 to 100 of about 120,368 (286)
Stochastic kinetics of a single headed motor protein: dwell time distribution of KIF1A [PDF]
EPL (Europhysics Letters), 93 (2011) 59004, 2010 KIF1A, a processive single headed kinesin superfamily motor, hydrolyzes Adenosine triphosphate (ATP) to move along a filamentous track called microtubule. The stochastic movement of KIF1A on the track is characterized by an alternating sequence of pause and translocation.
arxiv +1 more source
Advanced Genetics, EarlyView.Lung cancer is the leading cause of cancer‐related mortality worldwide. Among its types, non‐small cell lung cancer (NSCLC) accounts for the majority of cases. This study focuses on investigating genetic mutations that may influence the response to gemcitabine, a chemotherapy drug commonly used to treat this condition.
Ghassan Saod Saleh +3 more
wiley +1 more source
On inotropic effects of UTP in the human heart
Heliyon, 2019 Uridine 5′-triphosphate (UTP) exerts a positive inotropic effect (PIE) in isolated electrically driven isolated right atrial trabeculae carneae from patients undergoing heart surgery.
J. Neumann, B. Hofmann, U. Gergs
doaj
High-Fidelity DNA Sensing by Protein Binding Fluctuations [PDF]
Phys Rev Lett. 2004 Dec 17;93(25):258103, 2010 One of the major functions of RecA protein in the cell is to bind single-stranded DNA exposed upon damage, thereby triggering the SOS repair response.We present fluorescence anisotropy measurements at the binding onset, showing enhanced DNA length discrimination induced by adenosine triphosphate consumption.
arxiv +1 more source
iMetaOmics, EarlyView.This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu +8 more
wiley +1 more source
BioTechniques, 2009 Use of RNA affinity chromatography is commonly used to identify RNA binding proteins that interact with specific RNA cis-elements that function in post-transcriptional gene regulation.
Ruben H. Hovhannisyan, Russ P. Carstens
doaj +1 more source
P2Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]
, 2019 P2Y receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on P2Y Receptors [3, 5]) are activated by the endogenous ligands ATP, ADP, uridine triphosphate, uridine diphosphate and UDP-glucose.
Abbracchio, Maria-Pia +17 more
core +2 more sources
Phytotherapy Research, EarlyView.This study suggests that maslinic acid treatment protected intestinal mucosa and ameliorated gut inflammation, accompanied with significantly reduced inflammatory cytokines and Th cell infiltration and subset differentiation. In vitro, maslinic acid suppressed Th cell proliferation and differentiation, regulated cell cycle distribution, and decreased ...
Dan Li +8 more
wiley +1 more source
Experimental Biology and Medicine, 1968 SummaryAdenosine, adenosine triphosphate, inosine triphosphate and uridine triphosphate were administered iv in 100 mg doses to intact and adrenalectomized dogs to test the ability of these compounds to increase the plasma volume. Only adenosine triphosphate was found to be effective.
W. W. Swingle, A. J. Swingle
openaire +3 more sources
Pyrimidine biosynthesis is not an essential function for trypanosoma brucei bloodstream forms [PDF]
, 2013 <p>Background: African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite.</p> <p>Methodology/Principal ...
A Hofer +51 more
core +3 more sources