Results 101 to 110 of about 126,321 (267)
P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents [PDF]
The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Barnard, EA +3 more
core
SummaryAdenosine, adenosine triphosphate, inosine triphosphate and uridine triphosphate were administered iv in 100 mg doses to intact and adrenalectomized dogs to test the ability of these compounds to increase the plasma volume. Only adenosine triphosphate was found to be effective.
W W, Swingle, A J, Swingle
openaire +2 more sources
Cardiac bioenergetic and metabolic perturbations in late‐stage Leigh syndrome. Whole‐body NDUFS4 loss severely impairs cardiac complex I activity and respiration, shifting reliance to complex II and reducing glycolytic, TCA, and amino acid‐derived energy‐generating substrates in the heart.
Karin Terburgh +2 more
wiley +1 more source
In vitro Assessment of RNA Polymerase I Activity
In eukaryotic cells transcriptional processes are carried out by three different RNA polymerases: RNA polymerase I which specifically transcribes ribosomal RNA (rRNA), RNA polymerase II which transcribes protein-coding genes to yield messenger RNAs ...
Marzia Govoni
doaj +1 more source
Bioinspired catalysts: Synthesis, characterisation and some applications [PDF]
Our recent work concerning the synthesis, characterisation and some applications of bioinspired electron-transfer catalysts is reviewed in this contribution.
Pálinkó, István
core
Nucleosided derived antibiotics to fight microbial drug resistance: New utilities for an established class of drugs? [PDF]
Novel antibiotics are urgently needed to combat the rise of infections due to drug-resistant microorganisms. Numerous natural nucleosides and their synthetically modified analogues have been reported to have moderate to good antibiotic activity against ...
Ferrari, Valentina +2 more
core +1 more source
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg +3 more
wiley +1 more source
Roles of transcription factors, RBPA and SIGF, in the mycobacterium tuberculosis [PDF]
The mechanism of prokaryotic transcription has been characterized primarily in the classic system, Escherichia coli, and cannot be confidently extended to include other prokaryotic species, such as those of the Actinobacteria phylum.
Pope, Steven Scott
core +1 more source
Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death [PDF]
The purinergic signalling system, which uses purines and pyrimidines as chemical transmitters, and purinoceptors as effectors, is deeply rooted in evolution and development and is a pivotal factor in cell communication.
A Gartland +139 more
core +2 more sources
Nucleotides: Structure and Properties [PDF]
Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core +1 more source

