Results 121 to 130 of about 126,321 (267)

Differential Effects of Purinergic Signaling in Gastric Cancer-Derived Cells Through P2Y and P2X Receptors

Frontiers in Pharmacology, 2019
Gastric cancer (GC) is the one of the most prevalent cancers and one of the leading causes of cancer-induced deaths. Previously, we found that the expression of purinergic P2Y2 receptor (P2Y2R) is increased in GC samples as compared to adjacent healthy ...
María José Hevia, Patricio Castro, Patricio Castro, Katherine Pinto, Mauricio Reyna-Jeldes, Felipe Rodríguez-Tirado, Claudia Robles-Planells, Sebastián Ramírez-Rivera, Juan Andrés Madariaga, Juan Andrés Madariaga, Felipe Gutierrez, Javier López, Javier López, Marcelo Barra, Marcelo Barra, Erwin De la Fuente-Ortega, Giuliano Bernal, Claudio Coddou   +17 more
doaj   +1 more source

Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release [PDF]

, 2017
Bone cells constitutively release ATP into the extracellular environment where it acts locally via P2 receptors to regulate bone cell function. Whilst P2Y2 receptor stimulation regulates bone mineralisation, the functional effects of this receptor in ...
Arnett, T R, Gueneri, D, Hajjawai, M O, Orriss, I R, Patel, J J, Shaw, K   +5 more
core   +2 more sources

Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells

Journal of Lipid Research, 2003
Lysophosphatidic acid (LPA) is a receptor-active lipid mediator with a broad range of biological effects. Ovarian cancer cells synthesize LPA, which promotes their motility, growth, and survival.
Céline Luquain, Anurag Singh, Lixin Wang, Vishwanathan Natarajan, Andrew J. Morris   +4 more
doaj   +1 more source

Depression of presynaptic excitation by the activation of vanilloid receptor 1 in the rat spinal dorsal horn revealed by optical imaging

Molecular Pain, 2006
In this study, we show that capsaicin (CAP) depresses primary afferent fiber terminal excitability by acting on vanilloid receptor 1 (TRPV1 channels) of primary afferent fibers in adenosine 5'-triphosphate (ATP)- and temperature-dependent manner using ...
Ikeda Hiroshi, Kusudo Kei, Murase Kazuyuki   +2 more
doaj   +1 more source

Synthesis and Turnover of Mitochondrial Ribonucleic Acid in HeLa Cells: the Mature Ribosomal and Messenger Ribonucleic Acid Species Are Metabolically Unstable [PDF]

, 1981
The synthesis rates and half-lives of the individual mitochondrial ribosomal ribonucleic acid (RNA) and polyadenylic acid-containing RNA species in HeLa cells have been determined by analyzing their kinetics of labeling with [5-^3H]-uridine and the ...
Attardi, Giuseppe, Gelfand, Robert
core  

Effects of pH on Olfactory Behaviours in Male Shore Crabs, Carcinus maenas

Animals
The effects of climate change are becoming more apparent, predominantly concerning the impacts of ocean acidification on calcifying species. Many marine organisms rely on chemical signals for processes such as foraging for food, predator avoidance, or ...
Hannah Ohnstad, Amber Marie Jones, Bethany Howard, Paula Schirrmacher, Helga D. Bartels-Hardege, Jörg Detlef Hardege   +5 more
doaj   +1 more source

Characterization of GDP-mannose Pyrophosphorylase from Escherichia Coli O157:H7 EDL933 and Its Broad Substrate Specificity

, 2005
GDP-mannose pyrophosphorylase gene (ManC) of Escherichia coli (E. coli) O157 was cloned and expressed as a highly soluble protein in E. coli BL21 (DE3). The enzyme was subsequently purified using hydrophobic and ion exchange chromatographies. ManC showed
Hwang, Bum-Yeol, Kang, Young Bok (Abraham), Kim, Byung-Gee, Lee, Kwang-Won, Lee, Tek-Hyung, Park, Sung-Soo, Yang, Yung-Hun   +6 more
core  

Photoaffinity labelling with P3-(4-azidoanilido)uridine 5′-triphosphate identifies Gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis [PDF]

, 2000
Zlatka Kostova, David M. Rancour, Anant K. Menon, Peter Orlean   +3 more
openalex   +1 more source

Human adipose‐derived multipotent stromal cells enriched with IL‐10 modRNA improve diabetic wound healing: Trigger the macrophage phenotype shift

Bioengineering & Translational Medicine
Diabetic wounds present a significant challenge in regenerative medicine due to impaired healing, characterized by prolonged inflammation and deficient tissue repair, primarily caused by a skewed pro‐inflammatory macrophage phenotype.
Yuxin Zhang, Wei Wang, Liang Chen, Heng Wang, Dong Dong, Jingjing Zhu, Yu Guo, Yiqun Zhou, Tianyi Liu, Wei Fu   +9 more
doaj   +1 more source

Note on the Transphosphorylation Reaction between Uridine Monophosphate and Adenosine Triphosphate. [PDF]

, 1955
Agnete Munch‐Petersen, Anders Ehrenberg, Ragnar Lundén, Harald Prydz   +3 more
openalex   +1 more source