Results 121 to 130 of about 120,368 (286)
Adenylate effects on protein phosphorylation in the interenvelope lumen of pea chloroplasts [PDF]
, 1989 A 64-kilodalton (kDa) protein, situated in the lumen between the inner and outer envelopes of pea (Pisum sativum L.) chloroplasts (Soll and Bennett 1988, Eur. J.
A.M. Edelman +23 more
core +1 more source
The antiepileptic potential of nucleosides [PDF]
, 2014 Despite newly developed antiepileptic drugs to suppress epileptic symptoms, approximately one third of patients remain drug refractory. Consequently, there is an urgent need to develop more effective therapeutic approaches to treat epilepsy. A great deal
Dobolyi, Á. +3 more
core +1 more source
Targeting cytochrome C oxidase in mitochondria with Pt(II)-porphyrins for Photodynamic Therapy [PDF]
, 2010 Mitochondria are the power house of living cells, where the synthesis of the chemical "energy currency" adenosine triphosphate (ATP) occurs. Oxidative phosphorylation by a series of membrane protein complexes I to IV, that is, the electron transport chain, is the source of the electrochemical potential difference or proton motive force (PMF) of protons
arxiv +1 more source
British Journal of Pharmacology, Volume 182, Issue 13, Page 2950-2967, July 2025.Background and Purpose Platelet function during inflammation is dependent on activation by endogenous nucleotides acting on purinergic receptors. The P2Y14 receptor has been reported to be expressed on platelets and is involved in leukocyte recruitment during inflammation.
Md Monir Hossain +6 more
wiley +1 more source
The Scientific World Journal, 2012 The α-chemokine stromal derived factor 1 (SDF-1), which binds to the CXCR4 and CXCR7 receptors, directs migration and homing of CXCR4+ hematopoietic stem/progenitor cells (HSPCs) to bone marrow (BM) and plays a crucial role in retention of these cells in
Mariusz Z. Ratajczak +3 more
doaj +1 more source
ChemBioChem, Volume 26, Issue 11, June 3, 2025.In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout +1 more
wiley +1 more source
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. [PDF]
, 1987 Primary human monocyte-derived macrophages (MDM) were shown to have diminished deoxynucleoside kinase activities compared to T lymphoblasts, and a reduced ability to phosphorylate dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity ...
Carson, DA, Kornbluth, RS, Richman, DD
core
36 degree step size of proton-driven c-ring rotation in FoF1-ATP synthase [PDF]
arXiv, 2009 Synthesis of the biological "energy currency molecule" adenosine triphosphate ATP is accomplished by FoF1-ATP synthase. In the plasma membrane of Escherichia coli, proton-driven rotation of a ring of 10 c subunits in the Fo motor powers catalysis in the F1 motor. While F1 uses 120 degree stepping, Fo models predict a step-by-step rotation of c subunits
arxiv
ATP Hysteresis in Tripartite Synapses [PDF]
arXiv, 2009 Recent experimental studies strongly suggest the influence of glial purinergic transmission in the modulation of synaptic dynamics. By releasing adenosine triphosphate (ATP), which accumulates as adenosine, astrocytes tonically suppressed synaptic transmission. The delayed multi-step feedback of the glial adenosine with the neuron suggest the existence
arxiv
Angewandte Chemie, Volume 137, Issue 21, May 19, 2025.In dieser Studie wird eine Methode zur präzisen Kontrolle von Retinsäure‐Induzierbaren‐Gens‐I (RIG‐I) vorgestellt, einem Rezeptor des angeborenen Immunsystems, der, wenn er aktiviert wird, antitumorale Immunreaktionen und Zelltod von Krebszellen auslöst.
Sandra Anika Lewash +11 more
wiley +1 more source