Results 141 to 150 of about 120,368 (286)
Purinergic P2Y 2 receptors, G-protein coupled receptors that primarily couple with Gαq/11-proteins, are activated equipotently by adenosine-5′-triphosphate (ATP) and uridine-5′-triphosphate.
Kensuke Sakuma+4 more
doaj +1 more source
In this study, we show that capsaicin (CAP) depresses primary afferent fiber terminal excitability by acting on vanilloid receptor 1 (TRPV1 channels) of primary afferent fibers in adenosine 5'-triphosphate (ATP)- and temperature-dependent manner using ...
Ikeda Hiroshi+2 more
doaj +1 more source
The Iron-Type Nitrile Hydratase Activator Protein Is A GTPase [PDF]
The Fe-type nitrile hydratase activator protein from Rhodococcus equi TG328-2 (ReNHase TG328-2) was successfully expressed and purified. Sequence analysis and homology modeling suggest that it is a G3E P-loop guanosine triphosphatase (GTPase) within the ...
Bennett, Brian+3 more
core +1 more source
Active transport: A kinetic description based on thermodynamic grounds [PDF]
We show that active transport processes in biological systems can be understood through a local equilibrium description formulated at the mesoscale, the scale to describe stochastic processes. This new approach uses the method established by nonequilibrium thermodynamics to account for the irreversible processes occurring at this scale and provides ...
arxiv
P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential [PDF]
P2Y receptors for extracellular nucleotides are coupled to activation of a variety of G proteins and stimulate diverse intracellular signaling pathways that regulate functions of cell types that comprise the central nervous system (CNS).
Erb, Laurie+3 more
core +1 more source
The Isolation of Uridine-5'-Triphosphate from Muscle. [PDF]
Rolf Bergkvist+3 more
openalex +1 more source
P2Y11 receptors : properties, distribution and functions [PDF]
The P2Y11 receptor is a G protein-coupled receptor that is stimulated by endogenous purine nucleotides, particularly ATP. Amongst P2Y receptors it has several unique properties; 1) it is the only human P2Y receptor gene that contains an intron in the ...
Kennedy, Charles
core +1 more source
5'-nucleotidases, nucleosides and their distribution in the brain: pathological and therapeutic implications [PDF]
Elements of the nucleoside system (nucleoside levels, 5'-nucleotidases (5'NTs) and other nucleoside metabolic enzymes, nucleoside transporters and nucleoside receptors) are unevenly distributed in the brain, suggesting that nucleosides have region ...
Dobolyi, Árpád+3 more
core
Diabetic wounds present a significant challenge in regenerative medicine due to impaired healing, characterized by prolonged inflammation and deficient tissue repair, primarily caused by a skewed pro‐inflammatory macrophage phenotype.
Yuxin Zhang+9 more
doaj +1 more source
Regulation of hamster carbamoyl-phosphate synthase II by 5-phospho-α-d-ribosyl 1-diphosphate and uridine 5′-triphosphate [PDF]
Stephen D. Lyons+1 more
openalex +3 more sources