Results 231 to 240 of about 126,321 (267)

Functional effects of uridine triphosphate on human skinned skeletal muscle fibers

Canadian Journal of Physiology and Pharmacology, 1998
Chemically skinned human skeletal muscle fibers were used to study the effects of uridine triphosphate (UTP) on the tension-pCa relationship and on Ca2+uptake and release by the sarcoplasmic reticulum (SR). Total replacement (2.5 mM) of adenosine triphosphate (ATP) with UTP (i) displaced the tension-pCa relationship to the left along the abcissae and ...
R, Vianna-Jorge, C F, Oliveira, Y, Mounier, G, Suarez-Kurtz   +3 more
openaire   +2 more sources

Lactose synthetase assay: Uridine triphosphate inhibition of interfering hydrolase activity

Analytical Biochemistry, 1969
Abstract The presence of nonspecific UDP-galactose hydrolases in mammary tissue homogenates interferes with the radioactive assays of the A and B components of lactose synthetase. Uridine triphosphate was added to assay incubation mixtures and was found to effectively inhibit the hydrolase activity with a minimal influence on the specific A and B ...
openaire   +2 more sources

uridine triphosphate

Catalysis from A to Z, 2020
D. Wu
semanticscholar   +1 more source

Ionic interaction of amiloride and uridine 5′-triphosphate in nebulizer solutions

Journal of Pharmaceutical Sciences, 2004
Combination therapy using nebulized amiloride hydrochloride and uridine-5'-triphosphate (UTP) trisodium salt aerosols has been investigated for the treatment of cystic fibrosis (CF). Amiloride in aqueous solution precipitates in the presence of UTP, reducing drug concentrations.
Ronald J, Pettis, Michael R, Knowles, Kenneth N, Olivier, Masha, Kazantseva, Anthony J, Hickey   +4 more
openaire   +2 more sources

Uridine-5′-triphosphate Protects Against Hepatic- Ischemic/Reperfusion Injury in Mice

Transplantation, 2009
Mitochondrial calcium overload triggers apoptosis and also regulates ATP production. ATP and uridine-5'-triphosphate (UTP) depletion from hepatic tissue after ischemia causes cell death. ATP and UTP binds to cell membranes of the hepatocytes through P2Y receptors.
Ziv, Ben-Ari, Orit, Pappo, Smadar, Yitzhaki, Yelena, Cheporko, Asher, Shainberg, Tova, Zinman, Amiram, Ravid, Romi, Zemel, Larisa, Bachmatov, Efrat, Kurtzwald, Eytan, Mor, Edith, Hochhauser   +11 more
openaire   +2 more sources

Validity and Safety of Sputum Induction by Inhaled Uridine 5 ′ -Triphosphate

American Journal of Respiratory and Critical Care Medicine, 2001
Inhalation of hypertonic saline during sputum induction causes bronchoconstriction. We studied the validity and safety of sputum induction by uridine 5'-triphosphate (UTP). Sputum was induced by a 5-min inhalation of hypertonic saline (3%) on Day 1 and UTP (5 mg/ml in 0.9% saline) on Days 8 and 15 in 16 healthy subjects and 16 patients with mild-to ...
J, Tamaoki, M, Kondo, H, Kuroda, K, Aoshiba, K, Takeyama, J, Nakata, A, Nagai   +6 more
openaire   +2 more sources

URIDINE-5'-TRIPHOSPHATE

Journal of the American Chemical Society, 1953
S. H. Lipton, S. A. Morell, Alexander Frieden, Robert M. Bock   +3 more
openaire   +1 more source

Uridine Triphosphate Increases Proliferation of Human Cancerous Pancreatic Duct Epithelial Cells by Activating P2Y2 Receptor

Pancreas, 2013
Jihye Choi, Y. Ji, Dong Hyeon Lee
semanticscholar   +1 more source

[Vasoconstrictor effect of uridine triphosphate on pancreatic vascular bed].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1996
Purinoceptors have been classified according to their sensitivity to structural analogues of purines. In addition to the well established and widely distributed P2 purinoceptor subtypes (P2X and P2Y), the existence of "pyrimidine" or "nucleotide" receptors was proposed, which are sensitive to the pyrimidine nucleotide, uridine triphosphate (UTP ...
D, Hillaire-Buys, J, Chapal, P, Petit, M M, Loubatières-Mariani   +3 more
openaire   +1 more source

Mechanisms of secretion of ATP from cortical astrocytes triggered by uridine triphosphate

NeuroReport, 2003
A. Abdipranoto, G. J. Liu, E. Werry, M. Bennett   +3 more
semanticscholar   +1 more source