Results 31 to 40 of about 120,368 (286)

Metabolomic response of osteosarcoma cells to nanographene oxide-mediated hyperthermia [PDF]

Mater. Sci. Eng. C. 91, 340-348 (2018), 2021
Nanographene oxide (nGO)-mediated hyperthermia has been increasingly investigated as a localised, minimally invasive anticancer therapeutic approach. Near InfraRed (NIR) light irradiation for inducing hyperthermia is particularly attractive, because biological systems mostly lack chromophores that absorb in this spectral window, facilitating the ...
arxiv   +1 more source

Nanopore sequencing for N1-methylpseudouridine in RNA reveals sequence-dependent discrimination of the modified nucleotide triphosphate during transcription

bioRxiv, 2022
Direct RNA sequencing with a commercial nanopore platform was used to sequence RNA containing uridine (U), pseudouridine (Ψ), or N1-methylpseudouridine (m1Ψ) generated by in vitro transcription (IVT).
A. Fleming, C. Burrows
semanticscholar   +1 more source

Signaling of the Purinergic System in the Joint

Frontiers in Pharmacology, 2020
The joint is a complex anatomical structure consisting of different tissues, each with a particular feature, playing together to give mobility and stability at the body.
Carmen Corciulo, Carmen Corciulo, Bruce N. Cronstein, Bruce N. Cronstein   +3 more
doaj   +1 more source

NTPDase1 Modulates Smooth Muscle Contraction in Mice Bladder by Regulating Nucleotide Receptor Activation Distinctly in Male and Female

Biomolecules, 2021
Nucleotides released by smooth muscle cells (SMCs) and by innervating nerve terminals activate specific P2 receptors and modulate bladder contraction. We hypothesized that cell surface enzymes regulate SMC contraction in mice bladder by controlling the ...
Romuald Brice Babou Kammoe, Gilles Kauffenstein, Julie Pelletier, Bernard Robaye, Jean Sévigny   +4 more
doaj   +1 more source

Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]

, 2012
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz, BD Gill, C Crawford, Claire M. Peppiatt-Wildman, DR Ferguson, DR Schneider, EM Schwiebert, EW Inscho, EW Inscho, FQ Yang, G Burnstock, G Burnstock, G Burnstock, G Manfredi, G Xu, HA Neufeld, HA Praetorius, HA Praetorius, Hardyal S. Gill, HM Liebich, I Kugelgen von, I Kugelgen von, J Czarnecka, James Malone-Lee, JC Mathies, Jennifer C. Jacoby, JM Buescher, JO Svensson, JR Gever, K Sugaya, Kevin M. G. Taylor, KH Schram, KR Kim, LA Birder, LC Rump, LD Todorov, M Cichna, M Katayama, MA Bailey, N Ozer, N Yamaoka, NS Zur, P Bodin, P Vinas, PD Wilson, R Corriden, RC Calvert, Rebecca E. Birch, RL Cordell, S Tatur, S Wiener, SA Levesque, Scott S. P. Wildman, Toby S. Scott-Ward, V Jankowski, V Kumar, W Yu, Y Cheng, Y Sun, Y Sun, Y Zheng   +60 more
core   +2 more sources

UV resistance of nucleosides -- an experimental approach [PDF]

, 2020
The emergence of life on Earth is a highly discussed but still unsolved question. Current research underlines the importance of environments within close proximity to the Earth's surface as they can solve long-standing problems such as polymerization of nucleotides and phosphorylation of nucleosides.
arxiv   +1 more source

Enzymatic synthesis and reverse transcription of RNAs incorporating 2'-O-carbamoyl uridine triphosphate.

Chemical Communications, 2016
Enzymatic synthesis and the reverse transcription of RNAs containing 2'-O-carbamoyl uridine were evaluated. A mild acidic deprotection procedure allowed the synthesis of 2'-O-carbamoyl uridine triphosphate (UcmTP).
Yoshiaki Masaki, H. Ito, Y. Oda, Kazufumi Yamazaki, Nobuhiro Tago, Kentaro Ohno, Nozomi Ishii, Hirosuke Tsunoda, T. Kanamori, A. Ohkubo, M. Sekine, K. Seio   +11 more
semanticscholar   +1 more source

Dinucleoside polyphosphates : newly detected uraemic compounds with an impact on leucocyte oxidative burst [PDF]

, 2009
Background. Dinucleoside polyphosphates (NpnN) have pathophysiologic roles in cardiovascular disease and are newly detected uraemic retention solutes. They were retrieved in human plasma, tissues and cells.
Dhondt, Annemieke, Glorieux, Griet, Jankowski, Joachim, Jankowski, Vera, Schepers, Eva, Vanholder, Raymond   +5 more
core   +1 more source

P2Y receptors in GtoPdb v.2021.3 [PDF]

, 2021
P2Y receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on P2Y Receptors [3, 5, 192]) are activated by the endogenous ligands ATP, ADP, uridine triphosphate, uridine diphosphate and UDP-glucose.
Abbracchio, Maria-Pia, Boeynaems, Jean-Marie, Boyer, José L., Burnstock, Geoffrey, Ceruti, Stefania, Fumagalli, Marta, Gachet, Christian, Hills, Rebecca, Humphries, Robert G., Inoue, Kazu, Jacobson, Kenneth A., Kennedy, Charles, King, Brian F., Lecca, Davide, Miras-Portugal, Maria Teresa, Müller, Christa E., Ralevic, Vera, Weisman, Gary A.   +17 more
core   +2 more sources

Uridine triphosphate inhibits the proliferation of gastric cancer cells through Ca2+-mediated autophagy

Di-san junyi daxue xuebao, 2019
Objective To study the effect of uridine triphosphate (UTP) on the proliferation of gastric cancer cells and explore the underlying molecular mechanisms.
GAO Nannan, WAN Hanxing, DONG Hui, ZHAO Xiaoyan   +3 more
doaj   +1 more source