Results 141 to 150 of about 646,026 (337)

Landscape of peripheral immunity in patients with upper urinary tract urolithiasis and the underlying correlations with renal function

BMC Urology
Introduction Inflammatory and immunological responses are reported involved in the pathogenesis and progression of obstructive nephropathy (ON). This study was designed to investigate the characteristics of peripheral immunity in patients with upper ...
Subo Qian, Yongdong Pan, Quan Li, Liying Zhang, Liujian Duan, Yan Xu, Jianwei Cao, Xingang Cui, Yunteng Huang   +8 more
doaj   +1 more source

PVC Nanoplastics Exposure Exacerbates Asthma through R‐Loop Accumulation and Subsequent STING Activation in Macrophages

Advanced Science, EarlyView.
Polyvinyl chloride (PVC) nanoplastics (NPs) are shown to aggravate allergic airway inflammation in asthma by triggering R‐loop accumulation and activating the cGAS‐STING pathway in macrophages. This study reveals a novel immunotoxic mechanism linking environmental plastic exposure to asthma pathogenesis and highlights potential molecular targets for ...
Qimei Bao, Yixing Huang, Mingcong Deng, Chunkai Zhang, Dan Zu, Hanyi He, Yangchan Hu, Yuke Zhong, Chen Liang, Haidong Liu, Wumin Dai, Yanhua He, Yaoshu Teng, Ji Jing, Yin Shi, Xiangdong Cheng, Zu Ye   +16 more
wiley   +1 more source

Retracted: Comparison of the Efficacy and Complications of Soft Ureteroscopy Lithotripsy and Percutaneous Nephrolithotomy in the Treatment of Urinary Calculi: A Systematic Review and Meta-Analysis. [PDF]

Comput Math Methods Med, 2023
Methods In Medicine CAM.
europepmc   +1 more source

Polyhalogenated Carbazole Impairs Dopaminergic Neurons through Dysregulation of Liquid–Liquid Phase Separation in Caenorhabditis elegans

Advanced Science, EarlyView.
Polyhalogenated carbazoles (PHCZ), persistent environmental contaminants, preferentially accumulate in neuronal tissues. Studies using Caenorhabditis elegans and human neuronal cell lines reveal that PHCZ induce dopaminergic neurodegeneration by promoting liquid–liquid phase separation of α‐synuclein, reducing condensate fluidity, impairing ...
Yuhang Luo, Hongbo Xu, Pei Peng, Xinhe Lu, Qian Zhou, Ziqing Gao, Cheng Tang, Hongyan Yin, Ying Cai, Gaga Mahai, Zhiqiang Zhu, Zuojun Liu, Hanzeng Li, Shunqing Xu   +13 more
wiley   +1 more source

Chronic hepatitis B virus infection increases the risk of upper urinary calculi. [PDF]

BMC Urol, 2022
Hou B, Lin C, Hao Z.
europepmc   +1 more source

Three Cases of Spontaneous Fracture of Urinary Calculi in the Bladder [PDF]

Gordon Southam
openalex   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Urolithiasis in Songklanagarind Hospital; southern Thailand

Journal of Health Science and Medical Research (JHSMR), 2002
Objective: To address the epidemiology of urolithiasis in Songklanagarind Hospital; southern Thailand. Materials and Methods: Over the four-year period, 1997 - 2000, 5,445 urolithiasis patients searching for treatment in Songklanagarind Hospital were ...
M Marikatat, A Apiwatgaroon, C Pripatnanont   +2 more
doaj  

Fragmentation of urinary calculi in vitro by burst wave lithotripsy.

Journal of Urology, 2015
A. Maxwell, B. Cunitz, W. Kreider, O. Sapozhnikov, R. Hsi, J. Harper, M. Bailey, Mathew D. Sorensen   +7 more
semanticscholar   +1 more source

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

Advanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu, Huitong Ruan, Xiaolin Zhang, Weihan Zheng, Muhetaierjiang Mutailifu, Ling Wang, Liu Yu, Ruijun Peng, Rui Zhao, Zihan Wang, Jie Xu, Shaochuan Li, Yaobin Wu, Wenguo Cui, Mujun Lu   +14 more
wiley   +1 more source