Results 211 to 220 of about 622,597 (277)
Animal Models and Experimental Medicine, EarlyView.Blood pressure increases immediately when the 2K2C rats (made with 0.3, 0.25, and 0.2 mm U‐shaped clips) regain consciousness from anesthesia. 100% of the rats develop hypertension on the day of 2K2C surgery. Blood pressure continues to rise, resulting in severe hypertension and organ damage to the brain, heart, aorta, and kidneys at 1, 2, 4, and 6 ...
Jia‐Sheng Tian +4 more
wiley +1 more source
Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy
Annals of Neurology, EarlyView.Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam +29 more
wiley +1 more source
Building a Bridge Between Ambient MS and LC‐MS by Non‐Exhaustive Microdesorption
Angewandte Chemie, EarlyView.A sequential analysis strategy was developed to integrate rapid ambient mass spectrometry (MS) screening with LC‐MS confirmation using a single solid‐phase microextraction (SPME) device. The approach involves an initial non‐exhaustive microdesorption for ambient MS screening, followed by a second desorption for LC‐MS confirmation of only the disputed ...
Wei Zhou, Janusz Pawliszyn
wiley +2 more sources
Advanced NanoBiomed Research, EarlyView.Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu +3 more
wiley +1 more source
An Electrochemical Sensor for Tenofovir Monitoring
Advanced NanoBiomed Research, EarlyView.A novel laser‐scribed graphene/ gold spiky nanostructures/molecularly imprinted polymer electrochemical sensor is developed for sensitive and selective detection of tenofovir (TFV) to support human immunodeficiency virus adherence monitoring. It showed a broad linear range (10 nM–200 μM), low detection limit (3 nM), and high recovery (92.5%–113%) in ...
Abdellatif Ait Lahcen, Gymama Slaughter
wiley +1 more source
Quantitative Analysis of Fluorescent Sensor Arrays
Analysis &Sensing, EarlyView.Fluorescent sensor arrays have great potential for the quantification of analytes in complex systems. Herein, statistical multivariate techniques and deep learning models to provide quantitative information from such arrays are reviewed. Fluorescent sensor arrays address the limitations of a single sensor by leveraging multiple sensing elements to ...
Karandeep Grover +3 more
wiley +1 more source
Predicting Abrasion Resistance in Thermoplastic Polyurethanes Using Machine Learning
Journal of Applied Polymer Science, EarlyView.Data‐driven prediction of TPU abrasion resistance using Gradient Boosting Regression (GBR), demonstrating superior performance through an ensemble of decision trees. ABSTRACT Abrasion resistance is a critical property of thermoplastic polyurethane (TPU), especially for applications in automotive, footwear, and medical devices where durability under ...
Sara Zahmatkesh +3 more
wiley +1 more source
Animal Research and One Health, EarlyView.Dietary selenium (Se) deficiency is recognized as a global problem, and exogenous Se supplementation can effectively enrich its levels in animal bodies. Offal tissues are equally important as meat in Se enrichment. Varying properties among Se species require information beyond total Se concentration to fully evaluate health risk/benefits.
Xiaoqing Guo +9 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective The objective of this study was to investigate the effect of prophylactic trimethoprim‐sulfamethoxazole (TMP‐SMX) on the incidence of serious infections in patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Methods This multicenter cohort study was designed to emulate a target trial that studied 296 patients with ...
Yun Kyu Kim +7 more
wiley +1 more source