PBLD Orchestrates the STING‐Mediated Antiviral Immune Response and Autoimmune Diseases
During viral infection, PBLD expression is downregulated, thereby subverting host antiviral defenses and promoting viral replication. This study identifies PBLD as a positive regulator of STING‐induced type I interferon activation and delineated the molecular network underlying PBLD‐mediated antiviral immunity and autoimmune pathogenesis, highlighting ...
Peili Hou +17 more
wiley +1 more source
Impact of remote follow-up under an intelligent medical collaboration model on health promotion and clinical outcomes in patients with urinary calculi. [PDF]
Yang Y +6 more
europepmc +1 more source
Single-Use vs. Reusable Digital Flexible Ureteroscope to Treat Upper Urinary Calculi: A Propensity-Score Matching Analysis. [PDF]
Huang F +9 more
europepmc +1 more source
Intra-individual Comparative Study of Dynamic and Pharmacocavernography [PDF]
Sommerkamp, H. +2 more
core +1 more source
Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards +8 more
wiley +1 more source
A Commentary on Effect of Early-Intervention Acupuncture on Pain Relief Among Emergency Department Patients with Suspected Acute Renal Colic Due to Urinary Calculi: Study Protocol for a Randomized Clinical Trial [Letter]. [PDF]
Dan C, Luyao F, RuiJie M.
europepmc +1 more source
A supramolecular gelatin‐based hydrogel adhesive was engineered for hemorrhagic cystitis management. It provides robust wet‐tissue adhesion, rapid hemostasis, sustained quercetin release, effectively restoring the bladder barrier via anti‐inflammatory and antioxidant actions.
Xu Cao +10 more
wiley +1 more source
Effect of Early-Intervention Acupuncture on Pain Relief Among Emergency Department Patients with Suspected Acute Renal Colic Due to Urinary Calculi: Study Protocol for a Randomized Clinical Trial. [PDF]
Wang X +12 more
europepmc +1 more source
Protease‐activated plasmonic nanosensors are demonstrated to noninvasively monitor antitumor T cell activity in tumors with anatomical information upon adoptive T cell transfer via ultrasound‐guided photoacoustic imaging. These nanosensors are actuated by granzyme B, a protease secreted by activated cytotoxic T cells during tumor cell killing, which ...
Myeongsoo Kim +10 more
wiley +1 more source
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen +5 more
wiley +1 more source

