Results 41 to 50 of about 31,977 (294)

ACVIM Small Animal Consensus Recommendations on the Treatment and Prevention of Uroliths in Dogs and Cats. [PDF]

open access: yes, 2016
In an age of advancing endoscopic and lithotripsy technologies, the management of urolithiasis poses a unique opportunity to advance compassionate veterinary care, not only for patients with urolithiasis but for those with other urinary diseases as well.
Adams, LG   +5 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Methuosis Inducer SGI‐1027 Cooperates with Everolimus to Promote Apoptosis and Pyroptosis by Triggering Lysosomal Membrane Permeability in Renal Cancer

open access: yesAdvanced Science
The mTOR inhibitor everolimus has been approved as a sequential or second‐line therapy for renal cell carcinoma (RCC). However, the development of drug resistance limits its clinical applications.
Yu Luo   +14 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

The clinical efficacy of novel semirigid ureteroscopy with a vacuum suction device for treatment of >10 mm upper ureteral stones and impacted calculus: implications for clinical practice

open access: yesFrontiers in Surgery
ObjectiveThe novel semirigid ureteroscopy with a vacuum suction device has been increasing in the treatment of urinary stones recently. This study aimed to evaluate its clinical efficacy for treating >10 mm upper ureteral stones and impacted calculus ...
Longhui Lai   +22 more
doaj   +1 more source

Antibiotic prophylaxis during extracorporeal shock wave lithotripsy in the prevention of urinary tract infections in patients with sterile urine before the procedure [PDF]

open access: yes, 2011
Introduction: There are controversies in the literature regarding the need and the duration of antibiotic prophylaxis in patients with extracorporeal shock wave lithotripsy (ESWL), who had a negative urine culture before the operation.
Balmehd, M.   +3 more
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Bladder acellular matrix graft: in vivo functional properties of the regenerated rat bladder. [PDF]

open access: yes, 1999
The purpose of this study was to determine whether the rat urinary bladder augmented by an acellular matrix graft can restore the bladder's low-pressure reservoir function and preserve normal micturition.
Dahiya, R   +6 more
core  

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

Percutaneous Ureteric Stricture Dilation (PCUSD) [PDF]

open access: yes, 1997
Ureteric stricture dilation as an interventional uroradiological technique was initiated locally in March 1991. In ureteric dilation two approaches are feasible.
Cutajar, Lino   +4 more
core  

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