Results 51 to 60 of about 541,110 (246)

Spontaneous Upper Urinary Tract Rupture Caused by Ureteric Stones: Clinical Characteristics and Validation of a Radiological Classification System [PDF]

, 2021
Carolina Bebi, Matteo Giulio Spinelli, Gianpaolo Lucignani, Pierpaolo Biondetti, Laura Martinetti, Irene Fulgheri, E. De Lorenzis, Giancarlo Albo, Anna Maria Ierardi, Franco Palmisano, Andrea Salonia, Gianpaolo Carrafiello, E. Montanari, Luca Boeri   +13 more
openalex   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Effect of finerenone on proteinuria reduction in IgA nephropathy

Renal Failure
Background Recent studies have suggested a protective effect of finerenone on renal function and reduced the risk of cardiovascular events in patients with CKD and type 2 diabetes. However, its role in IgA nephropathy remains unknown. This study aimed to
Guizhen Yu, Meifang Wang, Xue Zhang, Juan Tao, Jie Zhao, Shanshan Liu, Suhan Zhou, Jingyi Zhou, Pingping Ren, Jun Cheng, Jianghua Chen   +10 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

Advanced Science
Antibody‐drug conjugates (ADCs) emerge as a potent cancer therapeutic strategy by enabling precise antigen recognition and efficient intracellular delivery of cytotoxic payloads. In this study, 7‐ethyl‐9‐fluorocamptothecin (A2), a camptothecin derivative,
Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang   +16 more
doaj   +1 more source

The clinical efficacy of novel semirigid ureteroscopy with a vacuum suction device for treatment of >10 mm upper ureteral stones and impacted calculus: implications for clinical practice

Frontiers in Surgery
ObjectiveThe novel semirigid ureteroscopy with a vacuum suction device has been increasing in the treatment of urinary stones recently. This study aimed to evaluate its clinical efficacy for treating >10 mm upper ureteral stones and impacted calculus ...
Longhui Lai, Longhui Lai, Yuanfeng Zhang, Yuanfeng Zhang, Yingru Wang, Enguang Yang, Guangrui Fan, Chaohu Chen, Kang Yao, Wenzhao Zhang, Wenzhao Zhang, Yongfei Liu, Yongfei Liu, Kai Zhu, Kai Zhu, Meixuan Ding, Meixuan Ding, Jinchun Xing, Zhiping Wang, Peide Bai, Tao Wang, Bin Chen, Jun Mi   +22 more
doaj   +1 more source

Application of the postnatal urinary tract dilation classification system to predict the need for surgical intervention among neonates and young infants [PDF]

, 2022
Jisun Hwang, Pyeong Hwa Kim, Hee Mang Yoon, Sang Hoon Song, Ah Young Jung, Jin Seong Lee, Young Ah Cho   +6 more
openalex   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Current perspectives and trends on the role of mitochondria in renal ischemia-reperfusion injury from 2005 to 2024: a bibliometric analysis and literature review

Frontiers in Physiology
BackgroundRenal ischemia-reperfusion injury (RIRI) represents a leading cause of acute kidney injury (AKI). Mitochondria, serving as the central organelles for cellular energy metabolism and signal transduction, play a pivotal role in the pathogenesis of
Rui Yan, Rui Yan, Rui Yan, Yalong Zhang, Yalong Zhang, Yalong Zhang, Zewen Li, Zewen Li, Zewen Li, Kunpeng Li, Kunpeng Li, Kunpeng Li, Jiangwei Man, Jiangwei Man, Jiangwei Man, Li Yang, Li Yang, Li Yang   +17 more
doaj   +1 more source