Results 31 to 40 of about 19,779,561 (150)

Ubiquitination regulates autophagy in cancer: simple modifications, promising targets

Journal of Translational Medicine
Autophagy is an important lysosomal degradation process that digests and recycles bio-molecules, protein or lipid aggregates, organelles, and invaded pathogens.
Yihui Wu, Yifei Chen, Xianyan Tian, Genbao Shao, Qiong Lin, Aiqin Sun   +5 more
doaj   +1 more source

Schisandrin B Attenuates Renal Fibrotic Remodeling in Association with Restoration of a PPARα-Related Tubular Fatty-Acid Oxidation Program

Biomedicines
Background: Renal ischemia–reperfusion injury (RIRI) is a major cause of acute kidney injury (AKI) and contributes to delayed graft function and progression toward chronic kidney disease.
Yun Deng, Changhong Xu, Jiaxuan Ma, Rui Yan, Yalong Zhang, Hao Wang, Kangyu Wang, Jiangwei Man, Li Yang   +8 more
doaj   +1 more source

The application of genetic testing technology in kidney transplantation: precision matching, non-invasive monitoring and personalized management

Frontiers in Immunology
Kidney transplantation remains the treatment of choice for patients with end-stage renal disease, yet its long-term success continues to face major challenges, including organ shortage, rejection, and drug toxicity.
Yalong Zhang, Yalong Zhang, Hao Wang, Hao Wang, Rui Yan, Rui Yan, Kangyu Wang, Kangyu Wang, Jiangwei Man, Jiangwei Man, Li Yang, Li Yang   +11 more
doaj   +1 more source

Analysis of total urinary catecholamines by liquid chromatography: methodology, routine experience and clinical interpretations of results [PDF]

, 1983
A simple routine method is described for simultaneous assay of total urinary adrenaline, noradrenaline and dopamine. The catecholamines are pre-purified on a small ion-exchange column, separated by reversed phase ion-pair liquid chromatography, and are ...
Schleicher, E. D., Kees, Frieder K., Wieland, O. H.   +2 more
core   +1 more source

Research advances on the urinary microbiome in non-infectious urinary tract diseases: from community composition to clinical prospects

Frontiers in Cellular and Infection Microbiology
IntroductionWith the rapid development of 16S rRNA sequencing and metagenomic technologies, the traditional concept of sterile urine has been completely overturned, and a diverse urinary microbiome has been identified even in healthy individuals ...
Yalong Zhang, Yalong Zhang, Hao Wang, Hao Wang, Rui Yan, Rui Yan, Kangyu Wang, Kangyu Wang, Jiangwei Man, Jiangwei Man, Li Yang, Li Yang   +11 more
doaj   +1 more source

Studies on the clinical significance of nonesterified and total cholesterol in urine [PDF]

, 1981
Gas-liquid chromatographic determinations of nonesterified and total urinary cholesterol were performed in 137 normals, 264 patients with various internal diseases without evidence of neoplasias or diseases of the kidney or urinary tract, 497 patients ...
Stadler, Alexander, Wallner, J., Eiermann, W., Jüngst, Dieter, Pickel, A., Marx, Franz J., Karl, Hans Josef   +6 more
core   +1 more source

Autophagy-related biological targets and network mechanisms of juglone against bladder cancer

Journal of Cancer Research and Clinical Oncology
Objective This study aimed to explore juglone’s mechanism in inducing autophagy and apoptosis in bladder cancer (BLCA) via network pharmacology and experimental validation.
Yuanfeng Zhang, Enguang Yang, Xinyu Zhang, Ze Zhang, Guoxin Huang, Baoyuan Tang, Chaohu Chen, Longhui Lai, Zixu Pei, Yonghai Zhang, Zhiping Wang   +10 more
doaj   +1 more source

PA-MSHA improves prognosis of patients undergoing radical cystectomy: a retrospective cohort study using inverse probability of treatment weighting

Frontiers in Immunology
ObjectiveTo observe the effect of Pseudomonas aeruginosa mannose-sensitive hemagglutinin (PA-MSHA) on the prognosis and the incidence of lymphatic leakage in patients undergoing radical cystectomy (RC).MethodA total of 129 patients who underwent RC in ...
Xiaohua Zhang, Zixu Pei, Jinglei Ren, Jing Shi, Wenjun Lu, Yuan Shui, Wentao Ma, Luyang Zhang, Hui Ding, Yunxin Zhang, Junqiang Tian, Zhiping Wang   +11 more
doaj   +1 more source

TRIM28 drives immune evasion via PARP1 SUMOylation and NAD+ depletion in clear cell renal cell carcinoma

Journal for ImmunoTherapy of Cancer
Background Immune checkpoint blockade (ICB) therapy has demonstrated significant clinical potential in a variety of cancers; however, its efficacy in clear cell renal cell carcinoma (ccRCC) remains suboptimal.
Yang Liu, Jing Xiong, Xiangpeng Zhan, Hongji Hu, Hao Wan, Fuchun Zheng, Luyao Chen, Xiaoqiang Liu, Xingang Cui, Songhui Xu, Bin Fu   +10 more
doaj   +1 more source

MR urography after low-dose diuretic injection in the evaluation of urinary tract obstruction

, 2003
Purpose: To evaluate the diagnostic capability of the MR-urography with low-dose diuretic injection in the evaluation of urinary tract obstruction. Methods and Materials: 55 patients suffering symptoms by obstructive uropathy underwent MR examination ...
M. Di Pietro, MR urography after low dose diuretic injection in the evaluation of urinary tract obstruction L. Zugaro, DI CESARE, Ernesto, MASCIOCCHI, CARLO, A. Catalucci, VICENTINI, Carlo   +5 more
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