Results 41 to 50 of about 561,554 (159)

A novel necroptosis-related genes signature to predict prognosis and treatment response in bladder cancer

Frontiers in Molecular Biosciences
BackgroundNecroptosis, a form of programmed inflammatory cell death, plays a crucial role in tumor development, necrosis, metastasis, and immune response. This study aimed to explore the role of necroptosis in BLCA and construct a new prognostic model to
Dongnuan Yao, Dongnuan Yao, Dongnuan Yao, Weitao Yu, Weitao Yu, Weitao Yu, Xueming Ma, Xueming Ma, Xueming Ma, Junqiang Tian, Junqiang Tian, Junqiang Tian   +11 more
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Comprehensive analysis of phagocytosis regulatory genes in bladder cancer: implications for prognosis and immunotherapy

Frontiers in Molecular Biosciences
BackgroundBladder cancer is a common malignant tumor of the urinary system. Its incidence and mortality rates are on the rise, and the existing treatment methods are difficult to meet the prognostic needs of patients. Phagocytosis plays a crucial role in
Xueming Ma, Xueming Ma, Xueming Ma, Dongnuan Yao, Dongnuan Yao, Dongnuan Yao, Weitao Yu, Weitao Yu, Weitao Yu, Gongping Wu, Gongping Wu, Gongping Wu, Chengwei Fan, Chengwei Fan, Chengwei Fan, Junqiang Tian, Junqiang Tian, Junqiang Tian   +17 more
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In-depth exploration and initial clinical practice of the ratio of endoscope-sheath diameter theory: smaller flexible ureteroscope with smaller ureteral access sheath

BMC Urology
Objectives To assess the outcomes of combining a 7.5Fr flexible ureteroscope (fURS) with a 10/12F ureteral access sheath (UAS) through a comprehensive in vitro and in vivo evalu-ation. Methods We conducted a comparative analysis, evaluating the impact of
Haowen Gu, Pengfei Qin, Jian Shan, Guohai Xie, Jiasheng Hu, Qiang Li, Ting Huang, Jingyu Shi, Yue Cheng, Zejun Yan, Li Fang   +10 more
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Macrophage Phenotypic Reprogramming and Renal Fibrosis: From Mechanistic Insights to Targeted Therapy

Xiehe Yixue Zazhi
Renal fibrosis represents the core pathway through which chronic kidney disease progresses to end-stage renal failure. Therapeutic strategies targeting renal fibrosis provide an important approach for clinically mitigating the transition from acute ...
ZHU Jiahao, XU Lubin, CHEN Limeng
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Obinutuzumab in Refractory Membranous Nephropathy: A Case Series

Kidney Medicine
Rationale & Objective: Membranous nephropathy (MN), recognized as an autoimmune kidney disease, responds well to anti-CD20 monoclonal antibodies. Obinutuzumab, a type Ⅱ humanized anti-CD20 and immunoglobulin G1 Fc-optimized monoclonal antibody, when ...
Yuxin Lin, Quan Han, Liangliang Chen, Yaomin Wang, Pingping Ren, Guangjun Liu, Lan Lan, Xin Lei, Jianghua Chen, Fei Han   +9 more
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Ultra-low-dose rituximab is effective for the treatment of patients with minimal change disease - A retrospective study

Journal of the Formosan Medical Association
Background purpose: Rituximab (RTX),an anti-CD20 monoclonal antibody can effectively treat minimal change disease (MCD),with low toxicity and a reduced steroid dosage. The optimal dosage of RTX for treating MCD remains unclear.
Chang Wang, Man-Zhu Zhang, Ling-Xu Li, Xiao-Ying Yun, Chun-miao Chen, Fei-fei Wang, Bing Li   +6 more
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Association between folate and glutamine metabolism and prognosis of kidney cancer

Frontiers in Nutrition
BackgroundRecent studies have shown that folate metabolism might influence cancer progression by regulating mitochondrial metabolism and glutamine is involved in the development and progression of several malignancies.
Jiaxuan Qin, Jiaxuan Qin, Jiaxuan Qin, Jiaxuan Qin, Chaoyue Ouyang, Chaoyue Ouyang, Chaoyue Ouyang, Chaoyue Ouyang, Xuan Zhuang, Xuan Zhuang, Xuan Zhuang, Xuan Zhuang   +11 more
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Global burden of benign prostatic hyperplasia, urinary tract infections, urolithiasis, bladder cancer, kidney cancer, and prostate cancer from 1990 to 2021

Military Medical Research
Background The burden of common urologic diseases, including benign prostatic hyperplasia (BPH), urinary tract infections (UTI), urolithiasis, bladder cancer, kidney cancer, and prostate cancer, varies both geographically and within specific regions.
Hao Zi, Meng-Yang Liu, Li-Sha Luo, Qiao Huang, Peng-Cheng Luo, Hang-Hang Luan, Jiao Huang, Dan-Qi Wang, Yong-Bo Wang, Yuan-Yuan Zhang, Ren-Peng Yu, Yi-Tong Li, Hang Zheng, Tong-Zu Liu, Yu Fan, Xian-Tao Zeng   +15 more
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Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio
Chemotherapy remains the main treatment for muscle‐invasive bladder cancer (BLCA) despite drug resistance and lack of target drugs greatly limiting long‐term survival of patients.
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
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Piezo channels in the urinary system: Correspondence. [PDF]

Exp Mol Med, 2023
Hu S, Yao X.
europepmc   +1 more source