Results 21 to 30 of about 465,397 (164)

Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection

Cell Reports
Summary: Urinary tract infections (UTIs) commonly afflict people with diabetes. To better understand the mechanisms that predispose diabetics to UTIs, we employ diabetic mouse models and altered insulin signaling to show that insulin receptor (IR) shapes
Laura Schwartz, Kristin Salamon, Aaron Simoni, Tad Eichler, Ashley R. Jackson, Matthew Murtha, Brian Becknell, Andrew Kauffman, Sarah Linn-Peirano, Natalie Holdsworth, Vidhi Tyagi, Hancong Tang, Steve Rust, Hanna Cortado, Irina Zabbarova, Anthony Kanai, John David Spencer   +16 more
doaj   +1 more source

Urinary Tract Infection and Microbiome

Diagnostics, 2023
Urinary tract infection is one of the most common bacterial infections and can cause major burdens, not only to individuals but also to an entire society. Current knowledge of the microbial communities in the urinary tract has increased exponentially due
Dong Soo Kim, Jeong Woo Lee
doaj   +1 more source

Obesity promotes urinary tract infection by disrupting bladder focal adhesion kinase signaling

iScience
Summary: Obesity is a significant public health concern associated with numerous health risks. Infections are a major complication of obesity, but the mechanisms driving increased infection risk remain unclear. Using a diet-induced obesity mouse model in
Laura Schwartz, Kristin Salamon, Aaron Simoni, Israel Cotzomi-Ortega, Yuriko Sanchez-Zamora, Sarah Linn-Peirano, Preeti John, Juan de Dios Ruiz-Rosado, Ashley R. Jackson, Xin Wang, John David Spencer   +10 more
doaj   +1 more source

ALGORITHM FOR THE EVALUATION OF CHILDREN WITH SUSPECTED URINARY TRACT ANOMALIES

Slovenska pediatrija, 2023
In the present review article “Algorithm for the evaluation of children with suspected urinary tract anomalies”, an updated algorithm for evaluation of children in whom urinary tract anomalies are suspected is presented.
Tanja Kersnik Levart, Robert Kordič
doaj   +1 more source

Ribonucleases of Mice and Men: Unveiling the Roles of the RNase A Superfamily in Host Defence

Journal of Immunology Research
Antimicrobial peptides and proteins (AMPs) constitute ancient host defence mechanisms to preserve tissue sterility and protect the host from infectious diseases.
Raúl Anguita, Yusuf Ali, Brian Becknell, Ester Boix   +3 more
doaj   +1 more source

PROFILE OF PATIENTS WITH URINARY TRACT STONE AT UROLOGY DEPARTMENT OF SOETOMO GENERAL HOSPITAL SURABAYA IN JANUARY 2016-DECEMBER 2016

Jurnal Urologi Indonesia, 2020
Objective: To identify the profile of patients with urinary tract stones at the Urology Department of Soetomo General Hospital Surabaya in January 2016-December 2016.
Reza Kurniawan, Tarmono Djojodimedjo, Anny Setijo Rahayu   +2 more
doaj   +1 more source

Effect of retention time on renal function and kidney size in patients with indwelling DJ tubes

Scientific Reports
The impact of DJ tube retention time on renal function has received scant attention from researchers. Nevertheless, there is a plethora of clinical evidence indicating that protracted stent retention can result in renal insufficiency, or even renal ...
Qianhao Huang, Zhiyong Zhang, Yifan Huang, Tao Wang, Yuedong Chen   +4 more
doaj   +1 more source

The aldosteronoma resolution score predicts the prognosis of hypertension under two surgical procedures

Frontiers in Endocrinology
BackgroundPrimary aldosteronism (PA) is a leading cause of secondary hypertension, and aldosterone-producing adenoma (APA) is the most prevalent subtype. Surgical intervention is the primary treatment modality.
Yifan Huang, Yifan Huang, Qianhao Huang, Yijie Xie, Yijie Xie, Chaoyue Ouyang, Yuedong Chen, Yuedong Chen, Chao Huang   +8 more
doaj   +1 more source

Management of patients with posterior urethral valves “from the fetus to adolescence”: French national diagnostic and care protocol (NDCP)

Orphanet Journal of Rare Diseases
Posterior urethral valves (PUV) are congenital anomalies characterized by the persistence of mucosal folds in the urethra, leading to various degrees of obstruction.
Alaa El-Ghoneimi, Luke Harper, Ugo Maria Pierucci, Thomas Blanc, Jonathan Rosenblatt, Nicolas Sananes, Sophie Dreux, Marianne Alison, Fred Avni, Stéphane Decremer, Veronique Baudouin, Sayaka Oguchi, Dan Baruch, Pascale Rolland-Santan, Hedyeh Nadafi-Stoeffel, Cécile Bonnet, Annabel Paye-Jaouen, Eliane Raffet, Lise Natio, Berengere Desprez, Delphine Demede, Marc David Leclair, Matthieu Peycelon   +22 more
doaj   +1 more source

BRCA2 mutations in familial breast cancer with prostate cancer: a case report and literature review

Frontiers in Oncology
Prostate cancer (PCa) is the second most common tumor in men globally. Its etiology has been attributed to multiple factors, including age and ethnicity, with family history identified as a significant risk factor.
Zhengsheng Liu, Zhengsheng Liu, Qianhao Huang, Meixuan Ding, Tao Wang, Yuedong Chen, Yuedong Chen, Kaiyan Zhang, Kaiyan Zhang   +8 more
doaj   +1 more source