Results 11 to 20 of about 480,284 (168)

Generation of induced pluripotent stem cell line, NCHi027-A, from a female child with Posterior Cloaca (Type B)

Stem Cell Research
Cloaca is an ultra-rare severe anorectal malformation in females where the gastrointestinal, genital, and urologic systems converge. Posterior Cloaca (Type B) is an extremely rare specific variant, where the urogenital sinus opens just anterior to the ...
Cintia E. Gomez Limia, Karunya Albert, Chaitrali Atre, Kusum Basnet, Darria L. Streeter, Nathalia G. Amado, Linda A. Baker   +6 more
doaj   +1 more source

Generation of induced pluripotent stem cell line, NCHi028-A, from a male child with Prune Belly Syndrome

Stem Cell Research
Prune belly syndrome (PBS) is a rare, multi-system congenital myopathy mainly affecting males, whose genetic basis is still being explored. Phenotypically, its morbidity spans from mild to lethal, and PBS cases manifest three cardinal pathological ...
Cintia E. Gomez Limia, Karunya Albert, Kusum Basnet, Chaitrali Atre, Hudaa Malik, Darria L. Streeter, Nathalia G. Amado, Linda A. Baker   +7 more
doaj   +1 more source

Murine Ribonuclease 6 Limits Bacterial Dissemination during Experimental Urinary Tract Infection

Journal of Innate Immunity
Introduction: The ribonuclease (RNase) A superfamily encodes cationic antimicrobial proteins with potent microbicidal activity toward uropathogenic bacteria.
Hanna Cortado, Macie Kercsmar, Birong Li, Gabriela Vasquez-Martinez, Sudipti Gupta, Christina Ching, Gregory Ballash, Israel Cotzomi-Ortega, Yuriko I. Sanchez-Zamora, Ester Boix, Diana Zepeda-Orozco, Ashley R. Jackson, John David Spencer, Juan de Dios Ruiz-Rosado, Brian Becknell   +14 more
doaj   +1 more source

PPARγ promotes urothelial remodeling during urinary tract obstruction

Experimental and Molecular Medicine
Urinary tract obstruction (UTO) is a common cause of kidney injury that can result in chronic kidney disease and end-stage renal disease. Heterogeneity in the extent of obstructive renal damage in humans with UTO implies the existence of unknown ...
Mohammad El-Harakeh, Felipe Rodriguez-Tirado, Andrew J. Hardman, Alexa Miehls, Oumoulkhairy Camara, Kelly M. Grounds, Glenis Tocaj, Macie Kercsmar, Birong Li, Xin Wang, Brian Becknell, Ashley R. Jackson   +11 more
doaj   +1 more source

Urinary Tract Infections [PDF]

Antibiotics, 2014
Urinary tract infections (UTI) are among the most frequently acquired infections in the community, but also in hospitals and other health care institutions, causing a huge amount of antibiotic consumption. During the last decade we have seen significant changes in the field of urinary tract infections regarding causative pathogens and antibiotic ...
Truls E. Bjerklund Johansen, Kurt G. Naber   +1 more
openaire   +3 more sources

Concentration of novel urinary tract infection biomarkers in neonates

Scientific Reports
Urinary tract infections (UTIs) are a common comorbidity in hospitalized neonates. The current UTI diagnostics have several limitations including invasive collection of urinary samples to ensure sterility, risk of contamination and lack of consensus ...
Maria Jebbia, Sudipti Gupta, Brett G. Klamer, Leeann Pavlek, Christina B. Ching, Tahagod H. Mohamed, Brian Becknell   +6 more
doaj   +1 more source

Redo Laparoscopic Pyeloplasty in Infants and Children: Feasible and Effective

Frontiers in Pediatrics, 2020
Purpose: To determine the feasibility and effectiveness of redo laparoscopic pyeloplasty among patients with failed previous pyeloplasty, specifically examining rates of success and complications.Materials and Methods: We retrospectively reviewed the ...
Hamdan Al-Hazmi, Hamdan Al-Hazmi, Matthieu Peycelon, Matthieu Peycelon, Matthieu Peycelon, Elisabeth Carricaburu, Elisabeth Carricaburu, Gianantonio Manzoni, Gianantonio Manzoni, Khalid Fouda Neel, Khalid Fouda Neel, Liza Ali, Liza Ali, Christine Grapin, Christine Grapin, Christine Grapin, Annabel Paye-Jaouen, Annabel Paye-Jaouen, Alaa El-Ghoneimi, Alaa El-Ghoneimi, Alaa El-Ghoneimi   +20 more
doaj   +1 more source

PTEN modulates urinary tract infection susceptibility and shapes urothelial antibacterial defenses

Life Science Alliance
This study reveals that PTEN modulates bladder urothelial immunity by regulating Akt, NFκB, and FAK signaling, shaping susceptibility to urinary tract infection.
Aaron Simoni, M Skye Bochter, Sarah Linn-Peirano, Kristin Salamon, Brian Becknell, Hanna Cortado, Ashley R Jackson, Laura Schwartz, John David Spencer   +8 more
doaj   +1 more source

Risk Indicators for Urinary Tract Infections in Low Risk Pregnancy and the Subsequent Risk of Preterm Birth

Antibiotics, 2021
Symptomatic urinary tract infections are associated with preterm birth. However, data on risk indicators for urinary tract infections are limited and outdated. The research is a secondary analysis.
Dominique E. Werter, Brenda M. Kazemier, Caroline Schneeberger, Ben W. J. Mol, Christianne J. M. de Groot, Suzanne E. Geerlings, Eva Pajkrt   +6 more
doaj   +1 more source

Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection

Cell Reports
Summary: Urinary tract infections (UTIs) commonly afflict people with diabetes. To better understand the mechanisms that predispose diabetics to UTIs, we employ diabetic mouse models and altered insulin signaling to show that insulin receptor (IR) shapes
Laura Schwartz, Kristin Salamon, Aaron Simoni, Tad Eichler, Ashley R. Jackson, Matthew Murtha, Brian Becknell, Andrew Kauffman, Sarah Linn-Peirano, Natalie Holdsworth, Vidhi Tyagi, Hancong Tang, Steve Rust, Hanna Cortado, Irina Zabbarova, Anthony Kanai, John David Spencer   +16 more
doaj   +1 more source