Results 31 to 40 of about 1,164,420 (256)
Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
Cell ReportsSummary: Urinary tract infections (UTIs) commonly afflict people with diabetes. To better understand the mechanisms that predispose diabetics to UTIs, we employ diabetic mouse models and altered insulin signaling to show that insulin receptor (IR) shapes
Laura Schwartz +16 more
doaj +1 more source
Antibiotics, 2021 Symptomatic urinary tract infections are associated with preterm birth. However, data on risk indicators for urinary tract infections are limited and outdated. The research is a secondary analysis.
Dominique E. Werter +6 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Obesity promotes urinary tract infection by disrupting bladder focal adhesion kinase signaling
iScienceSummary: Obesity is a significant public health concern associated with numerous health risks. Infections are a major complication of obesity, but the mechanisms driving increased infection risk remain unclear. Using a diet-induced obesity mouse model in
Laura Schwartz +10 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
The cost-benefit analysis of hazardous medical waste: A case study of a hospital
Journal of Environmental ScienceThis study aimed to identify safe disposal methods for hazardous medical waste generated by healthcare institutions, particularly government hospitals, and to assess its impact on public health and the environment using a cost-benefit analysis .
elshimaa Abdelaziz
doaj +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Ribonucleases of Mice and Men: Unveiling the Roles of the RNase A Superfamily in Host Defence
Journal of Immunology ResearchAntimicrobial peptides and proteins (AMPs) constitute ancient host defence mechanisms to preserve tissue sterility and protect the host from infectious diseases.
Raúl Anguita +3 more
doaj +1 more source
A study of urinary catheter encrustation in patients with Proteus urinary tract infection. [PDF]
, 2007 The most common cause of encrustation and blockage of long term urinary catheters is colonisation of the urinary tract by Proteus spp. However, the degree of encrustation experienced by those with Proteus colonisation differs markedly between ...
Mathur, S.
core
Healthcare-associated urinary tract infections in urology [PDF]
, 2021 The purpose of the present review is to report the incidence and characteristics of healthcare-associated urinary tract infections (HAUTIs) in urology with their microbiological and resistance patterns.
Medina-Polo, José +5 more
core +1 more source