Results 21 to 30 of about 547,544 (315)

Generation of induced pluripotent stem cell line, NCHi028-A, from a male child with Prune Belly Syndrome

Stem Cell Research
Prune belly syndrome (PBS) is a rare, multi-system congenital myopathy mainly affecting males, whose genetic basis is still being explored. Phenotypically, its morbidity spans from mild to lethal, and PBS cases manifest three cardinal pathological ...
Cintia E. Gomez Limia, Karunya Albert, Kusum Basnet, Chaitrali Atre, Hudaa Malik, Darria L. Streeter, Nathalia G. Amado, Linda A. Baker   +7 more
doaj   +1 more source

Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men [PDF]

, 2014
Context Although family studies have shown that male lower urinary tract symptoms (LUTS) are highly heritable, no systematic review exists of genetic polymorphisms tested for association with LUTS. Objective To systematically review and meta-analyze
Gonzalez-Maffe, J, Andrew Walley, Altaf Mangera, Bennett, PR, Phillip R. Bennett, Mangera, A, Ambrose, Chris, Cartwright, R, Palmer, T, Chapple, Christopher R., Tikkinen, KAO, Ambrose, C, Walley, A, Jarvelin, M-R, Bennett, Phillip R., Anna C. Kirby, Ganesh Thiagamoorthy, Rajan, Prabhakar, Pesonen, J, Rajan, P, Mangera, Altaf, Jori Pesonen, Thiagamoorthy, G, Kirby, AC, Khullar, V, Järvelin, Marjo Riitta, Pesonen, Jori, Tom Palmer, Chris Chapple, Chris Ambrose, Tikkinen, Kari A. O., Prabhakar Rajan, Juan Gonzalez-Maffe, Thiagamoorthy, Ganesh, Cartwright, Rufus, Kari A.O. Tikkinen, Vik Khullar, Chapple, Chris, Rufus Cartwright, Chapple, C, Kirby, Anna C., Marjo-Riitta Järvelin, Gonzalez-Maffe, Juan, Walley, Andrew, Jarvelin, Marjo-Riitta, Khullar, Vik, Palmer, Tom M., Palmer, Tom, Tikkinen, Kari A.O.   +48 more
core   +1 more source

PPARγ promotes urothelial remodeling during urinary tract obstruction

Experimental and Molecular Medicine
Urinary tract obstruction (UTO) is a common cause of kidney injury that can result in chronic kidney disease and end-stage renal disease. Heterogeneity in the extent of obstructive renal damage in humans with UTO implies the existence of unknown ...
Mohammad El-Harakeh, Felipe Rodriguez-Tirado, Andrew J. Hardman, Alexa Miehls, Oumoulkhairy Camara, Kelly M. Grounds, Glenis Tocaj, Macie Kercsmar, Birong Li, Xin Wang, Brian Becknell, Ashley R. Jackson   +11 more
doaj   +1 more source

Murine Ribonuclease 6 Limits Bacterial Dissemination during Experimental Urinary Tract Infection

Journal of Innate Immunity
Introduction: The ribonuclease (RNase) A superfamily encodes cationic antimicrobial proteins with potent microbicidal activity toward uropathogenic bacteria.
Hanna Cortado, Macie Kercsmar, Birong Li, Gabriela Vasquez-Martinez, Sudipti Gupta, Christina Ching, Gregory Ballash, Israel Cotzomi-Ortega, Yuriko I. Sanchez-Zamora, Ester Boix, Diana Zepeda-Orozco, Ashley R. Jackson, John David Spencer, Juan de Dios Ruiz-Rosado, Brian Becknell   +14 more
doaj   +1 more source

INJURIES OF THE URINARY TRACT [PDF]

Southern Medical Journal, 1916
n ...
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Concentration of novel urinary tract infection biomarkers in neonates

Scientific Reports
Urinary tract infections (UTIs) are a common comorbidity in hospitalized neonates. The current UTI diagnostics have several limitations including invasive collection of urinary samples to ensure sterility, risk of contamination and lack of consensus ...
Maria Jebbia, Sudipti Gupta, Brett G. Klamer, Leeann Pavlek, Christina B. Ching, Tahagod H. Mohamed, Brian Becknell   +6 more
doaj   +1 more source

Redo Laparoscopic Pyeloplasty in Infants and Children: Feasible and Effective

Frontiers in Pediatrics, 2020
Purpose: To determine the feasibility and effectiveness of redo laparoscopic pyeloplasty among patients with failed previous pyeloplasty, specifically examining rates of success and complications.Materials and Methods: We retrospectively reviewed the ...
Hamdan Al-Hazmi, Hamdan Al-Hazmi, Matthieu Peycelon, Matthieu Peycelon, Matthieu Peycelon, Elisabeth Carricaburu, Elisabeth Carricaburu, Gianantonio Manzoni, Gianantonio Manzoni, Khalid Fouda Neel, Khalid Fouda Neel, Liza Ali, Liza Ali, Christine Grapin, Christine Grapin, Christine Grapin, Annabel Paye-Jaouen, Annabel Paye-Jaouen, Alaa El-Ghoneimi, Alaa El-Ghoneimi, Alaa El-Ghoneimi   +20 more
doaj   +1 more source

Risk Indicators for Urinary Tract Infections in Low Risk Pregnancy and the Subsequent Risk of Preterm Birth

Antibiotics, 2021
Symptomatic urinary tract infections are associated with preterm birth. However, data on risk indicators for urinary tract infections are limited and outdated. The research is a secondary analysis.
Dominique E. Werter, Brenda M. Kazemier, Caroline Schneeberger, Ben W. J. Mol, Christianne J. M. de Groot, Suzanne E. Geerlings, Eva Pajkrt   +6 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source