Results 41 to 50 of about 752,211 (305)

Obesity promotes urinary tract infection by disrupting bladder focal adhesion kinase signaling

iScience
Summary: Obesity is a significant public health concern associated with numerous health risks. Infections are a major complication of obesity, but the mechanisms driving increased infection risk remain unclear. Using a diet-induced obesity mouse model in
Laura Schwartz, Kristin Salamon, Aaron Simoni, Israel Cotzomi-Ortega, Yuriko Sanchez-Zamora, Sarah Linn-Peirano, Preeti John, Juan de Dios Ruiz-Rosado, Ashley R. Jackson, Xin Wang, John David Spencer   +10 more
doaj   +1 more source

D-mannose: a promising support for acute urinary tract infections in women. A pilot study [PDF]

, 2016
Urinary tract infections still represent a significant bother for women and result in high costs to the health system. D-mannose is a simple sugar; it seems able to hinder bacteria adhesion to the urothelium.
BENEDETTI PANICI, PIERLUIGI, BRACCHI, CARLOTTA, COLAGIOVANNI, VANESSA, DOMENICI, LAVINIA, GIORGINI, MARGHERITA, MONTI, Marco, MUZII, LUDOVICO   +6 more
core  

Effect of sampling method and storage conditions on albumin, retinol-binding protein, and N-acetyl-β-D-glucosaminidase concentrations in canine urine samples [PDF]

, 2010
Urinary markers for renal dysfunction are gaining interest but effects of sampling method, storage conditions, and urinary tract inflammation or infection on these markers are unclear Therefore, the objectives of the current study were to determine the ...
Daminet, Sylvie, Duchateau, Luc, Maddens, Bert, Meyer, Evelyne, Smets, Pascale   +4 more
core   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

ALGORITHM FOR THE EVALUATION OF CHILDREN WITH SUSPECTED URINARY TRACT ANOMALIES

Slovenska pediatrija, 2023
In the present review article “Algorithm for the evaluation of children with suspected urinary tract anomalies”, an updated algorithm for evaluation of children in whom urinary tract anomalies are suspected is presented.
Tanja Kersnik Levart, Robert Kordič
doaj   +1 more source

Pathophysiology, Clinical Importance, and Management of Neurogenic Lower Urinary Tract Dysfunction Caused by Suprasacral Spinal Cord Injury [PDF]

, 2016
Management of persistent lower urinary tract dysfunction resulting from severe thoracolumbar spinal cord injury can be challenging. Severe suprasacral spinal cord injury releases the spinal cord segmental micturition reflex from supraspinal modulation ...
Granger, Nicolas, Hu, Hilary Z, Jeffery, ND   +2 more
core   +2 more sources

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

PROFILE OF PATIENTS WITH URINARY TRACT STONE AT UROLOGY DEPARTMENT OF SOETOMO GENERAL HOSPITAL SURABAYA IN JANUARY 2016-DECEMBER 2016

Jurnal Urologi Indonesia, 2020
Objective: To identify the profile of patients with urinary tract stones at the Urology Department of Soetomo General Hospital Surabaya in January 2016-December 2016.
Reza Kurniawan, Tarmono Djojodimedjo, Anny Setijo Rahayu   +2 more
doaj   +1 more source

Is a low sacral ratio associated with primary vesicoureteral reflux in children? [PDF]

, 2013
Introduction: The association of sacral anomalies with fecal incontinence and lower urinary tract dysfunction is known. The sacral ratio is proposed as a tool for evaluation of sacral development. The aim of this cross-sectional study was to evaluate the
Esfahani, S.T., Mehdizadeh, M., Rezaei-Hemami, M.   +2 more
core  

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source