Results 71 to 80 of about 1,164,420 (256)
Urinary cholesterol in cancer screening [PDF]
, 1982 Cholesterol determinations in morning urine samples were taken in 235 selected patients with a positive test for microscopic hematuria. Values ranged from 0.2 to 76.0 mg (median 5.5) in 23 patients with urologic malignancies and from 0.1 to 33.4 mg ...
Tauber, Roland +3 more
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Advanced Science, EarlyView.Through self‐supervised pretraining and supervised fine‐tuning on large‐scale cytology image datasets, CytoNet predicts lymph node metastasis and survival. Across independent cohorts, this multitask framework demonstrates robust performance, improves risk stratification beyond radiological assessment, and provides interpretable evidence to support ...
Guibin Hong +14 more
wiley +1 more source
Advanced ScienceThe mTOR inhibitor everolimus has been approved as a sequential or second‐line therapy for renal cell carcinoma (RCC). However, the development of drug resistance limits its clinical applications.
Yu Luo +14 more
doaj +1 more source
Immunology of urinary tract infections
, 2020 The urinary tract is constantly exposed to different microorganisms that colonize the gastrointestinal tract and the urinary tract is normally well prepared to resist infections by these microorganisms. This resistance to infection is mainly accomplished
Ortega Martell, JA
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Nigella sativa Linn. and lower urinary tract infection treatment [PDF]
, 2018 Lower urinary tract infection (UTIs) is very common diseases that occur in at least 60% of women. UTIs are caused by microorganisms, commonly Gram negative bacteria. Escherichia coli (E.coli) play role a most cases.
Utami, Amalia Tri
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Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
The Relation between Treated Maternal Urinary Tract Infection and Adverse Maternal, Prenatal Outcomes in Pregnant Women of Ardabil, Iran [PDF]
Background and Objective: Urinary tract infection is one of the most common bacterial infections during pregnancy and has also been implicated as a risk factor for adverse maternal and prenatal outcomes.
مرادی, شهلا +5 more
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Advanced Science, EarlyView.ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou +9 more
wiley +1 more source
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
Advanced Science, EarlyView.This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Urinary tract infection in an older patient: a case study and review
, 2023 This article will discuss and reflect on a case study involving the prescribing of nitrofurantoin, by a non-medical prescriber, for a suspected symptomatic uncomplicated urinary tract infection in a patient living in a care home. The focus will be around
Read, H. +3 more
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