Results 111 to 120 of about 940,512 (316)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Examining intraindividual variability of urinary gluten immunogenic peptides compared to the lactulose-mannitol ratio in healthy volunteers: implications for clinical assessment of intestinal permeability

Frontiers in Immunology
IntroductionThe intestinal barrier plays a crucial role in preventing the translocation of harmful substances. Intestinal permeability is commonly assessed using the lactulose-mannitol ratio (LMR) test, which measures absorption of non-metabolizable ...
Raquel Rodríguez-Ramírez, Raquel Rodríguez-Ramírez, María Auxiliadora Fernández Peralbo, Ángel Cebolla, Carolina Sousa   +4 more
doaj   +1 more source

Serum activities of liver enzymes in workers exposed to sub-TLV levels of dimethylformamide

International Journal of Occupational Medicine and Environmental Health, 2015
Objectives: The aim of this study has been to investigate serum activities of liver enzymes in workers exposed to sub-TLV levels of dimethylformamide (DMF). Material and Methods: Seventy-two workers and 72 healthy controls participated in the study.
Jinjiang He, Jie Liu, Yulin Kong, Weiwei Yang, Zengli Zhang   +4 more
doaj   +1 more source

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Urinary Metabolomics-Driven Discovery of Metabolic Markers and Molecular Subtyping in Liver Cancer

Frontiers in Bioscience-Landmark
Background: Primary liver cancer (PLC) exhibits a high incidence and mortality rate. Early diagnosis and effective treatment are crucial for improving patient survival rates.
Hemeng Wu, Hongsheng Lin, Fuli Long, Rongzhen Zhang, Minpeng Li, Yunyong Wang, Faming Shu, Yangwu Zhang, Mingfen Li, Xiaoling Zhou   +9 more
doaj   +1 more source

Excreção fracionada do cálcio e fósforo em novilhas nelore antes e durante a gestação Calcium and phosphorus fractional excretion in nellore before and during pregnancy

Pesquisa Agropecuária Brasileira, 2000
A avaliação do cálcio e do fósforo nutricional é difícil quando se usam concentrações séricas desses elementos, pois estas permanecem dentro de valores normais apesar de variações do conteúdo desses minerais na dieta, pela alta eficiência do processo de ...
ALEXANDRE SECORUN BORGES, BRENO PELOSO DE BARROS, ANA LIZ GARCIA ALVES, PAULO CÉSAR CIARLINE, PEDRO LUIZ BICUDO, AGUEMI KOHAYAGAWA   +5 more
doaj   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Microbiological Relevance of Candida in Urine Cultures

Journal of Fungi
The presence of Candida spp. in urine has traditionally been considered to be a colonization; however, in certain clinical circumstances, such as in critically ill patients, immunocompromised individuals, or those with chronic diseases, it gains greater ...
Leticia Castellano-Sánchez, Antonio Rosales-Castillo, Raquel Marcos-Rodríguez, María Carmen Olvera-Porcel, José María Navarro-Marí, José Gutiérrez-Fernández   +5 more
doaj   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source