Results 211 to 220 of about 1,044,595 (309)

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

Advanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye, Miaoru Han, Siqiao Tang, Zongxiang Zhang, Haichen Shen, Bingzhen Sun, Yan Zhang, Xiaodong Chu, Lijuan Deng, Chaoyang Zheng, Qingchun Huang, Kun Bao, Ronghua Zhang, Yong Wang, Fengwei Zhang, Xiaoli Chu   +15 more
wiley   +1 more source

Effect of Acupuncture on Urine Production and Storage in Prostate Cancer Survivors With Nocturia: Exploratory Analysis of a Randomized Clinical Trial. [PDF]

JU Open Plus
Booher AG, Mao J, Sandhu J, Ajay D, Carlsson SV, Laudone V, Morris MJ, Liou KT.   +7 more
europepmc   +1 more source

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

Advanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim, Na Yeon Han, Ayman Muzammal, Jae Hun Ahn, Changkeun Im, Sujin Kim, Sairan Eom, Choong Mo Kang, Ku Kang, Yong Jin Lee, Kyo Chul Lee, Michael K. Schultz, Dongyoul Lee   +12 more
wiley   +1 more source

Hybrid Molecular Lateral Flow Assay Targeting the lipL32 Gene for Rapid and Highly Sensitive Detection of Pathogenic <i>Leptospira</i>. [PDF]

Trop Med Infect Dis
Difa SA, Widoretno, Handayani FD, Yohda M, Zahrantiara R, Sukma CM, Wibowo YG, Sahlan M.   +7 more
europepmc   +1 more source

Non‐Invasive Assessment of Perineural Invasion Density: A Novel Marker for Prognosis and Treatment Stratification in Prostate Cancer

Advanced Science, EarlyView.
This study establishes perineural invasion density (PNID) as a superior prognostic marker in prostate cancer, outperforming conventional perineural invasion in predicting biochemical recurrence and radiographic progression. Concurrent β–blocker use is associated with favorable outcomes exclusively in High–PNID patients. An MRI–based deep learning model
Bohao Liu, Long Zhang, Weian Zhu, Meng Yang, Xiang Liu, Xiaoyang Li, Peng Qin, Zhengxu Lin, Qian Cai, Jiayu Zheng, Xiao Zhao, Chen Zou, Xuan Wen, Longhao Xu, Daqin Wu, Lin Zhang, Cuilian Zhang, Kaiwen Li, Chunhui Wang, Wenlong Zhong, Yun Luo   +20 more
wiley   +1 more source

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

Advanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng, Xiaohua Li, Shuo Li, Chungen Xing, Chun Cao   +4 more
wiley   +1 more source

Optimizing hydration in Chinese youth taekwondo athletes: evidence-based daily and training session-specific fluid intake recommendations. [PDF]

Front Nutr
Song G, Chen Y, Li J, Pan X, Sui H, Chen J, Lin Y, Yan Y.   +7 more
europepmc   +1 more source

ENDOTHELIN IN URINE

The Lancet, 1989
Berbinschi, A., Ketelslegers, Jean-Marie
openaire   +3 more sources

Nanocatalytic Immunotherapy Targeting Tumor‐Resident Intracellular Bacteria for Triple‐Negative Breast Cancer Treatment and Metastasis Suppression

Advanced Science, EarlyView.
Bacteria residing within tumor cells contribute to breast cancer progression, but few therapies target their elimination. FeSe2 nanosheets coated with cancer cell membranes accumulate in tumors and generate reactive oxygen species under ultrasound, killing tumor cells and their harbored bacteria at the same time.
Xiaojing Leng, Tao Jiang, Zhao Guo, Zhimin Zhang, Yihan Chen, Pan Li, Min Ge, Han Lin, Liang Zhang   +8 more
wiley   +1 more source

Lysosomal exoglycosidases as biomarkers of systemic diseases - what's new? [PDF]

Front Mol Biosci
Ptaszyńska-Sarosiek I, Sarosiek WW, Sarosiek GI, Charuta A, Maciejczyk M.   +4 more
europepmc   +1 more source