Results 241 to 250 of about 1,044,595 (309)

Short‐Term Outcomes of Transanal Total Mesorectal Excision for Rectal Cancer: A Multicenter Propensity Score‐Matched Analysis Comparing Patients With and Without Preoperative Neoadjuvant Therapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To evaluate the association between preoperative neoadjuvant therapy and short‐term outcomes of transanal total mesorectal excision for rectal cancer. Methods We retrospectively analyzed patients who underwent transanal total mesorectal excision at 26 Japanese institutions between 2012 and 2019.
Takafumi Shima, Hiroki Hamamoto, Takeru Matsuda, Ichiro Takemasa, Keitaro Tanaka, Toshiki Mukai, Jun Watanabe, Sang‐Woong Lee, Seiichiro Yamamoto, Takeshi Naitoh, Ta‐Ta‐Mi Study Group Collaborators from the Japan Society of Laparoscopic Colorectal Surgery, Akihiro Kondo, Akinobu Taketomi, Akiyoshi Kanazawa, Atsushi Ogura, Chikayoshi Tani, Gunpei Yoshimatsu, Hideki Endo, Hideya Kashihara, Hirokazu Suwa, Junichiro Kawamura, Kay Uehara, Kei Kimura, Keiichi Okano, Keiichiro Okuyama, Kenji Okita, Kiyoshi Maeda, Kohei Shigeta, Koji Okabayashi, Koya Hida, Masafumi Inomata, Masahiko Watanabe, Masaji Tani, Masataka Ikeda, Masatsune Shibutani, Masayoshi Iwamoto, Masayuki Ishii, Nobuki Ichikawa, Shigenori Honma, Shinichiro Mori, Shiro Terai, Suguru Hasegawa, Takeshi Okabayashi, Takuya Tokunaga, Tatsunari Fukuoka, Tatsuya Manabe, Tatsuya Shonaka, Tomonori Akagi, Toru Kuramoto, Toru Miyake, Toshikatsu Nitta, Toshiki Mukai, Yoshihito Ide, Yosuke Fukunaga, Yuki Murata, Yukinari Tokoro, Yukitoshi Todate, Yusaku Shogen   +57 more
wiley   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Brief Report: Hair Testing to Detect Long-term Methamphetamine Use in People Living With and Without HIV. [PDF]

J Acquir Immune Defic Syndr
Appa A, Javanbakht M, Spinelli M, Heise MJ, Steiner G, Okochi H, Gorbach P, Gandhi M, Bolanos R.   +8 more
europepmc   +1 more source

A Bioinspired Underwater Soft Robot for Active Intravesical Liquid Delivery and Mixing

Advanced Intelligent Systems, EarlyView.
A bioinspired underwater soft robot is reported that integrates an elastic strain energy‐driven soft robotic pump with a programmable flexible magnetic valve, enabling remotely controlled, programmable, and sustained liquid release and mixing. This functionality is enabled by the synergistic integration of elastic strain energy‐driven pumping and ...
Jacob Katona, Sage Bernstein, Boyang Xiao, Amie Zhang, Ellen Lu, Evan Ticknor, Jeffrey J. Tosoian, Xiaoguang Dong   +7 more
wiley   +1 more source

Final Analysis of the BRUIN Phase 1/2 Study Assessing the Safety and Efficacy of Pirtobrutinib Monotherapy in Patients With MCL

American Journal of Hematology, EarlyView.
ABSTRACT Pirtobrutinib, a highly selective, non‐covalent Bruton tyrosine kinase inhibitor (BTKi) previously demonstrated durable efficacy and tolerable safety following covalent (c) BTKi therapy in heavily pretreated relapsed/refractory (R/R) mantle cell lymphoma (MCL).
Michael L. Wang, Jonathon B. Cohen, Nirav N. Shah, Wojciech Jurczak, Pier Luigi Zinzani, Chan Y. Cheah, Chaitra S. Ujjani, Youngil Koh, Won Seog Kim, Sunita D. Nasta, Ian Flinn, Benoit Tessoulin, Shuo Ma, Alvaro J. Alencar, David J. Lewis, Jennifer A. Woyach, Kami J. Maddocks, Krish Patel, Yucai Wang, Joanna M. Rhodes, Constantine S. Tam, John F. Seymour, Hirokazu Nagai, Julie M. Vose, Bita Fakhri, Marc S. Hoffmann, Francisco Hernandez‐Ilizaliturri, Andrew D. Zelenetz, Anita Kumar, Talha Munir, Donald E. Tsai, Paolo Abada, Minna Balbas, Jian Li, Denise Wang, Lindsey E. Roeker, Toby A. Eyre   +36 more
wiley   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Obstructive nephropathy requiring dialysis secondary to genitourinary tuberculosis with concomitant pulmonary tuberculosis in an immunocompetent young adult: A case report. [PDF]

IDCases
Ghebremichael HT, Wakoya AD, Ayele MW, Teferi DA, Alemayehu TH.   +4 more
europepmc   +1 more source

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright, Maria B. Padua, Lindsey R. Helvaty, Kim L. McBride, Gabrielle Geddes, Vidu Garg, Seema R. Lalani, Stephanie Burns Wechsler, Jennelle C. Hodge, Benjamin J. Landis, Stephanie M. Ware   +10 more
wiley   +1 more source

Urine-based detection of <i>Leishmania donovani</i> antibodies using recombinant aurora kinase and otubain cysteine peptidase for noninvasive diagnosis of visceral leishmaniasis. [PDF]

J Clin Microbiol
Bhattacharyya A, Kamran M, Chhajer R, Ejazi SA, Rahman M, Goswami RP, Madhukar M, Das VNR, Das P, Pandey K, Ali N.   +10 more
europepmc   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source