From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
The Urine in Nervousness [PDF]
The Journal of Nervous and Mental Disease, 1913 n ...
openaire +2 more sources
Antibiotic prophylaxis during extracorporeal shock wave lithotripsy in the prevention of urinary tract infections in patients with sterile urine before the procedure [PDF]
, 2011 Introduction: There are controversies in the literature regarding the need and the duration of antibiotic prophylaxis in patients with extracorporeal shock wave lithotripsy (ESWL), who had a negative urine culture before the operation.
Balmehd, M. +3 more
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Improving and disaggregating N2O emission factors for ruminant excreta on temperate pasture soils [PDF]
, 2016 pre-printCattle excreta deposited on grazed grasslands are a major source of the greenhouse gas (GHG) nitrous oxide (N2O). Currently, many countries use the IPCC default emission factor (EF) of 2% to estimate excreta-derived N2O emissions.
Carolan, Rachael +7 more
core +1 more source
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Short term N2O losses in urine patches: a 15N labelling study [PDF]
, 2004 These results show that emission of N2O is greater when N is added as urine compared with mineral N. This can probably be explained by the presence of organic carbon compounds in the urine, which may fuel the N2O production.
Ambus, P.
core
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Effects of increasing cow urine deposition area on soil mineral nitrogen movement and pasture growth on a recent soil in the Manawatu region, New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Environmental Management at Massey University, Manawatū, Palmerston North, New Zealand [PDF]
, 2017 The cow urine patch is a major source of nitrate (NO3¯) leaching from grazed dairy pasture farms. Increasing the urine deposition area is a direct way of reducing the potential risk of this cause N leaching losses.
Romero Ramírez, Stefanía Yanina
core
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source