Results 71 to 80 of about 1,044,595 (309)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Human biomonitoring of neonicotinoid exposures: case studies after the use of a spray-agent to ornamental plants and a topical medication to pets

Frontiers in Public Health
Acetamiprid (ACE) and imidacloprid (IMI) are insecticides of global importance and are used as spray and watering agents for ornamental plants to control biting and sucking insects or as topical medications on pets to remove and control fleas.
Sonja A. Wrobel, Stephan Koslitz, Daniel Bury, Heiko Hayen, Holger M. Koch, Thomas Brüning, Heiko U. Käfferlein   +6 more
doaj   +1 more source

Urine-derived epithelial cell lines: a new tool to model fragile X syndrome (FXS)

, 2020
Fragile X syndrome (FXS) is an X-linked neurodevelopmental condition associated with intellectual disability and behavioral problems due to the lack of the Fragile X mental retardation protein (FMRP), which plays a crucial role in synaptic plasticity and
M Jasoliya (10091626), Flora Tassone (9483407), M Zafarullah (9972692)   +2 more
core   +1 more source

Detection and genotyping of human Papillomavirus in urine samples from unvaccinated male and female adolescents in Italy [PDF]

, 2013
The introduction of vaccination against Human Papillomavirus (HPV) in adolescent girls in 2006 has focused virological surveillance on this age group. As few studies have evaluated HPV infections in young populations, further data are needed in order to ...
Zotti, CM, Boccalini, Sara, Elisabetta Tanzi, Gasparini Roberto, Coppola Rosa Cristina, R. Gasparini, Rosa Cristina Coppola, Coppola, RC, Gasparini R, Paolo Castiglia, M. Martinelli, M. Martinese, Panatto D, Silvia Bianchi, Amicizia, D, Amicizia D, Paolo Bonanni, Zotti CM, Elena Rosanna Frati, Bianchi S, Bianchi, S, Martinelli, M, Castiglia Paolo, Bianchi Silvia, D. Panatto, Marianna Martinelli, Meloni, Angelo, Tanzi Elisabetta, Amicizia, Daniela, G. Masia, Masia Giuseppina, Zotti, Carla Maria, Bianchi, Silvia, Daniela Amicizia, Bonanni, Paolo, Martinese M, Martinese, M, Masia G, Castiglia, Paolo Giuseppino, Tanzi, Elisabetta, S. Bianchi, Morena Martinese, C. M. Zotti, P. Castiglia, Coppola R C, Boccalini, S, Amicizia Daniela, Boccalini S, Martinelli Marianna, Bonanni Paolo, Bonanni P, Panatto, Donatella, Panatto Donatella, Frati, ER, Tanzi E, Zotti Carla Maria, Martinelli, Marianna, Frati ER, Piana Andrea, Tanzi, E., Piana A, Martinese, Morena, Gasparini, Roberto, Gasparini, R, Castiglia P, Donatella Panatto, Meloni Angelo, Martinese Morena, Sara Boccalini, D. Amicizia, E. Tanzi, Andrea Piana, P. Bonanni, Panatto, D, Meloni, A, Frati, Elena Rosanna, Masia, Giuseppina, Piana, Andrea Fausto, Boccalini Sara, Giuseppina Masia, R. C. Coppola, A. Meloni, E.R. Frati, Angelo Meloni, S. Boccalini, Roberto Gasparini, Frati Elena Rosanna, Masia, G, A. Piana, Martinelli M, Coppola, Rosa Cristina, Meloni A, Carla Maria Zotti, Bonanni, P   +93 more
core   +2 more sources

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Determination of clostebol residues in the urine of slaughter animals using liquid chromatography–tandem mass spectrometry

Journal of Veterinary Research
Synthetic anabolic hormones, which may pose a potential risk to human health, should not be used in fattening food-producing animals. Because of the hormonal effects they cause, growth-promoting compounds are banned by legislation in the EU for use in ...
Matraszek-Żuchowska Iwona, Kłopot Alicja, Grzelak Justyna, Zdonek Paulina   +3 more
doaj   +1 more source

Lipoarabinomannan in urine during tuberculosis treatment: association with host and pathogen factors and mycobacteriuria. [PDF]

, 2012
BACKGROUND: Detection of lipoarabinomannan (LAM), a Mycobacterium tuberculosis (Mtb) cell wall antigen, is a potentially attractive diagnostic. However, the LAM-ELISA assay has demonstrated variable sensitivity in diagnosing TB in diverse clinical ...
Vogt, Monica, Middelkoop, Keren, Vogt Monica, Lawn Stephen D, Middelkoop Keren, Lawn, Stephen, Lawn, Stephen D, Robin Wood, Kreiswirth, Barry N., Bekker Linda-Gail, Stephen D Lawn, Racow, Kimberly, Racow Kimberly, Barry N Kreiswirth, Kreiswirth, Barry N, Wood Robin, Linda-Gail Bekker, Lawn, Stephen D., Monica Vogt, Kreiswirth Barry N, Kreiswirth, Barry, Bekker, Linda-Gail, Wood, Robin, Kimberly Racow, Keren Middelkoop   +24 more
core   +2 more sources

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Not all that is red is blood: a curious case of chromaturia

Clinical Case Reports, 2018
Key Clinical Message Hydroxocobalamin causes reddish discoloration of the urine, mimicking hematuria. Clinicians should be aware of this common side effect of the rarely used drug to prevent unnecessary consultations and work‐up. Additional benign causes
Abhilash Koratala, Gajapathiraju Chamarthi, Mark S. Segal   +2 more
doaj   +1 more source