Results 1 to 10 of about 1,542 (123)

Urine alkalization facilitates uric acid excretion [PDF]

Nutrition Journal, 2010
Background Increase in the incidence of hyperuricemia associated with gout as well as hypertension, renal diseases and cardiovascular diseases has been a public health concern.
Seyama Issei, Hakoda Masayuki, Kanbara Aya   +2 more
doaj   +5 more sources

The efficacy and safety of citrate mixture vs sodium bicarbonate on urine alkalization in Chinese primary gout patients with benzbromarone: a prospective, randomized controlled study [PDF]

Rheumatology, 2021
Abstract Objectives To compare the efficacy and safety of citrate mixture and sodium bicarbonate on urine alkalization in gout patients under benzbromarone treatment. Methods A prospective, randomized, parallel controlled trial was ...
Xiaomei Xue, Tony Merriman
exaly   +5 more sources

A prospective study on urine alkalization with an oral regimen consisting of sodium bicarbonate and acetazolamide in patients receiving high-dose methotrexate [PDF]

Cancer Management and Research, 2019
Daniel R Reed,1 Eric J Pierce,2 Jeremy M Sen,3 Michael K Keng11Division of Hematology/Oncology, Department of Medicine, University of Virginia, Charlottesville, VA, USA; 2Department of Medicine, University of Virginia, Charlottesville, VA, USA ...
Reed DR, Pierce EJ, Sen JM, Keng MK
doaj   +7 more sources

Detection of Novel Visible-Light Region Absorbance Peaks in the Urine after Alkalization in Patients with Alkaptonuria [PDF]

PLoS ONE, 2014
BACKGROUND: Alkaptonuria, caused by a deficiency of homogentisate 1,2-dioxygenase, results in the accumulation of homogentisic acid (2,5-dihydroxyphenylacetic acid, HGA) in the urine.
Makoto Kurano, Shinobu Inagaki, Ryunosuke Ohkawa   +2 more
exaly   +5 more sources

Effect of urine alkalization on urinary inflammatory markers in cystinuric patients [PDF]

CKJ: Clinical Kidney Journal
ABSTRACT Background Cystinuria is associated with a high prevalence of chronic kidney disease (CKD). We previously described a urinary inflammatory-protein signature (UIS), including 38 upregulated proteins, in cystinuric patients (Cys-patients), compared with healthy controls (HC).
, Vincent Jung, Caroline Prot-Bertoye
exaly   +4 more sources

Impact of adding urine alkalization therapy to xanthine oxidase inhibitor in gout management: a prospective cohort study [PDF]

Rheumatology
Abstract Objectives Gout patients frequently have decreased urine pH, related to metabolic syndrome (MetS) and chronic kidney disease. Here, we aimed to investigate whether the addition of urine alkalization to urate-lowering therapy (ULT) is associated with improvements in albuminuria, gout flares or
Chang-Gui Li, Can Wang
exaly   +4 more sources

Effects of adding urinary alkalizer citrate mixture to febuxostat in gout patients with combined-type hyperuricemia and low urine pH: a prospective cohort study [PDF]

Arthritis Research & Therapy
Background People with gout and combined-type hyperuricemia, defined as renal urate overload and renal urate under-excretion, have diminished responsiveness to urate-lowering therapy.
Kai Guo, Changgui Li, Robert Terkeltaub, Nicola Dalbeth, Xuefeng Wang, Xiaopeng Ji, Ying Chen, Lingling Cui, Zhen Liu, Xinde Li, Yuwei He, Jie Lu, Wenyan Sun, Lin Han, Hui Zhang, Aichang Ji, Mingshu Sun, Can Wang   +17 more
doaj   +4 more sources

Baseline urine pH is related to effective urine alkalization by short-term alkaline water supplementation: data from a self-controlled study in healthy Chinese volunteers following a systematic review and meta-analysis of literature. [PDF]

Transl Androl Urol, 2022
The outcomes of urine alkalization with alkaline water supplementation vary greatly across studies and therefore remain inconclusive, probably arising from differences in study design, ethnic group, and source of alkaline water, which needs further clarification. With a systematic review of literature, followed by an empirical observation among healthy
Zhang G, Deng T, Deng R, Sun X, He Y, Liu Z.   +5 more
europepmc   +5 more sources

Effect of alkalized urine on renal calculi in patients with gout: a protocol for a placebo-controlled, double-blinded randomized controlled trial [PDF]

Trials, 2021
Background The prevalence of renal calculi in patients with gout is high. Alkalized urine has been recommended by the 2020 European Association of Urology (EAU) guidelines to promote calculus dissolution. However, randomized controlled trials are lacking.
Ertao Jia, Haiqiong Zhu, Hongling Geng, Yadong Wang, Li Zhong, Shangwen Liu, Feng Lin, Jianyong Zhang   +7 more
doaj   +3 more sources

Effects of alkalization therapy on hepatocellular carcinoma: a retrospective study

Frontiers in Oncology, 2023
BackgroundIn hepatocellular carcinoma (HCC) patients, is difficult to prevent recurrence even when remission is achieved. In addition, even with the advent of drugs that are effective for the treatment of HCC, a satisfactory extension of patient survival
Reo Hamaguchi, Masahide Isowa, Hiromasa Morikawa   +2 more
exaly   +3 more sources