Results 41 to 50 of about 1,561 (140)

Acute rhabdomyolysis in hepatitis-associated aplastic anemia patient undergoing allogeneic hematopoietic stem-cell transplantation: case report and literature review

European Journal of Medical Research, 2022
Background Hepatitis-associated aplastic anemia (HAAA) is a specific type of aplastic anemia, and hematopoietic stem-cell transplantation (HSCT) is recommended as the first-line.
Yuzhu Li, Yilei Hong, Yingying Shen, Qi Liu, Ying Chen, Keding Shao, Yiping Shen, Baodong Ye, Dijiong Wu   +8 more
doaj   +1 more source

EFFICACY OF FUROSEMIDE IN METHOTREXATE CLEARANCE IN PATIENTS TREATED WITH HIGH DOSE METHOTREXATE

Hematology, Transfusion and Cell Therapy, 2022
Objective: Methotrexate was first used in 1947 as a chemotherapeutic drug in the treatment of acute lymphoblastic leukemia (ALL). Methotrexate has been extensively explored as an anticancer drug since that time.
Saqib Khan, Tariq Muhammad, Yasmin Abdul Rashid   +2 more
doaj   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, Volume 13, Issue 16, 18 March 2026.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Typical course of cystinuria leading to untypical complications in pregnancy: A case report and review of literature

Frontiers in Medicine, 2023
Cystinuria is a rare genetic disorder inherited by an autosomal recessive pattern which affects the transmembrane transporter for the base amino acid cystine. It has a general prevalence of 1 in 7000 with demographic variations.
Ema Ivandic, Marjan Maric, Vesna Elvedi-Gasparovic, Margareta Fistrek Prlic, Lovro Lamot, Lovro Lamot, Bojan Jelakovic, Bojan Jelakovic, Ivana Vukovic Brinar, Ivana Vukovic Brinar   +9 more
doaj   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Cancer can be suppressed by alkalizing the tumor microenvironment: the effectiveness of “alkalization therapy” in cancer treatment

Oncologie
The abnormal metabolism of cancer cells, referred to as the Warburg effect, creates acidic tumor microenvironments (TME) that can contribute to treatment resistance and cancer progression.
Kachi Shion, Hamaguchi Reo, Narui Ryoko, Morikawa Hiromasa, Okamoto Toshihiro, Wada Hiromi   +5 more
doaj   +1 more source

Interstitial Cystitis/Bladder Pain Syndrome in Men

Neurourology and Urodynamics, Volume 45, Issue 1, Page 26-31, January 2026.
ABSTRACT Aims In April 2025, the Wake Forest Institute for Regenerative Medicine hosted a Global Consensus meeting on interstitial cystitis/bladder pain syndrome (IC/BPS) in Winston‐Salem, NC. The goal of this meeting was to establish attainable targets in phenotyping, diagnosis, and biomarkers for IC/BPS.
Madeline Snipes, Wyatt Whitman, Michel Pontari, Jennifer Anger, Michael Samarinas, Rajesh Taneja   +5 more
wiley   +1 more source

Reno-protective effects of oral alkalizing agents in chronic kidney disease with aciduria: protocol for a randomized cohort study

BMC Nephrology, 2020
Background Aciduria caused by urinary excretion of acidic metabolic wastes produced in daily life is known to be augmented in patients with chronic kidney disease (CKD). To evaluate the reno-protective effect of oral alkalizing agents for the improvement
Michiaki Abe, Tetsuya Akaishi, Mutsumi Shoji, Takuhiro Yamaguchi, Takashi Miki, Fumitoshi Satoh, Shin Takayama, Satomi Yamasaki, Kazuhiko Kawaguchi, Hiroshi Sato, Tadashi Ishii, Sadayoshi Ito, CKOALA study group   +12 more
doaj   +1 more source

Effect of Potassium Citrate on Prevention of Recurrence and Expulsion of Residual Fragments of Calcium Oxalate renal Stones [PDF]

Trends in Pharmaceutical Sciences, 2019
Considering potassium citrate ability to induce urine alkalization, it may be useful in the treatment and prevention of renal stone formation. The aim of this study was to evaluate the potassium citrate preventive effect on recurrence and also expulsion ...
mohammad mehdi Hosseini, Shohre Alipour, Mohammadali Ashraf, kian Omidbakhsh   +3 more
doaj   +1 more source

Oral Regimen for Urine Alkalization in Patients Receiving High Dose Methotrexate during a National Shortage of Intravenous Sodium Bicarbonate

Blood, 2018
Abstract Background: High dose methotrexate (MTX) is an important agent in the prevention and treatment of cancer in the central nervous system. Administration of this drug requires alkalization of the urine, which traditionally includes the use of intravenous (IV) sodium bicarbonate (bicarb).
Daniel R Reed, Jeremy M Sen, Eric J Pierce, Maria C Nicolais, Michael K Keng   +4 more
openaire   +1 more source