Results 61 to 70 of about 1,561 (140)

LNP‐mediated in vivo base editing corrects Agxt to cure primary hyperoxaluria type 1

Clinical and Translational Medicine, Volume 15, Issue 11, November 2025.
The base editor precisely corrected the Agxt gene with high efficiency in PH1 rats. LNP‐delivered ABE normalised urinary oxalate levels and prevented calculus formation. This study identified the minimal Agxt correction efficiency required for urinary oxalate normalisation.
Dexin Zhang, Rui Zheng, Zhoutong Chen, Xi Chen, Lei Yang, Yanan Huo, Yining Zhao, Jiaxin Huang, Dan Zhang, Shuming Yin, Dali Li, Hongquan Geng   +11 more
wiley   +1 more source

Exploring the Spatial Limits of Extracellular Vesicles‐Mediated Intercellular Communication

Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
ABSTRACT Extracellular vesicles (EVs) are biological nanovectors that retain molecular signatures of their cells of origin and mediate intercellular communication, resulting in ideal platforms for the development of diagnostic tools and bio‐inspired drug delivery technologies.
Federico Colombo, Kartik Nimkar, Erienne Grace Norton, Francesca Lovat, Emanuele Cocucci   +4 more
wiley   +1 more source

Synthesis, Properties, and Typical Applications of MXene‐Based Heterostructure Materials

Advanced Materials Interfaces, Volume 12, Issue 19, October 6, 2025.
In recent years, MXene‐based heterostructure materials have achieved fruitful outcomes in multiple aspects. However, a comprehensive and systematic summary of MXene‐based heterostructures is still absent. This review summarizes the performance characteristics, synthesis methods, and the latest research progress of MXene heterostructures in several ...
Baoquan Xiao, Zelin Gao, Hengbiao Zhang, Jiantao Zhang, Shiyuan Wang, Gang Long, Shenghu Wei, Jixing Huang, Runqi Yao, Xingdong Jiang, Fei Ma, Xusheng Xia, Liyun Ding   +12 more
wiley   +1 more source

Surface Treatment With Cell Culture Medium: A Biomimetic Approach to Enhance the Resistance to Biocorrosion in Mg and Mg‐Based Alloys—A Review

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 9, September 2025.
ABSTRACT In contemporary orthopedics, the demand for temporary biodegradable bone implants has driven the development of materials capable of supporting bone regeneration while gradually resorbing in the body, thereby eliminating the need for secondary removal surgery.
Vida Khalili, Sannakaisa Virtanen, Aldo R. Boccaccini   +2 more
wiley   +1 more source

Estimates of Urinary Calcium Excretion in Dogs With and Without Calcium Oxalate Urolithiasis

Journal of Veterinary Internal Medicine, Volume 39, Issue 5, September/October 2025.
ABSTRACT Background Fractional excretion of calcium (FeCa) and urine calcium‐to‐creatinine ratios (UCaCr) estimate hypercalciuria, but more data are needed on how well they discriminate between dogs with and without CaOx urolithiasis. Objective To determine the performance of FeCa and UCaCr in predicting CaOx urolith status.
Danielle E. LaVine, Emily L. Coffey, Jody P. Lulich, Jennifer L. Granick, Eva Furrow   +4 more
wiley   +1 more source

Encrusting cystitis caused by Corynebacterium urealyticum: literature review

Вестник урологии
Encrusting cystitis represents an exceptionally rare form of chronic bladder inflammation, characterized by bladder wall calcification. The predominant causative agent is Corynebacterium urealyticum, a gram-positive multidrugresistant bacillus.
O. Yu. Nesterova, V. K. Dzitiev, N. I. Sorokin, A. A. Strigunov, A. G. Korobova, I. A. Zhestkov, I. D. Burlakov, A. A. Kamalov   +7 more
doaj   +1 more source

Effect of Pumpkin Seed Milk on Physicochemical, Textural, Rheological, Antioxidant, and Sensory Properties of Pudding

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
This study investigates the physicochemical, textural, rheological, antioxidant and sensory properties of puddings made with different ratios of milk obtained from pumpkin seeds. It was concluded that using up to 50% pumpkin seed milk in pudding production was sensory acceptable.
Başak Aygün, Ahmet Emirmustafaoğlu
wiley   +1 more source

Establishing the Interrelations of the Laboratory Parameters in the Gut-Kidney Axis in Cats with Signs of Triple Phosphate Urolithiasis

Ветеринарная патология
Introduction. Efficient treatment of the feline urolithiasis much depends on the early diagnosis of the disease, however, the diagnostic algorithm of this type of pathology is extremely poor due to the various reasons, in particular, it does not take ...
T. M. Ushakova, T. N. Derezina, V. S. Chichilenko   +2 more
doaj   +1 more source

Recent Advances in the Diagnosis and Management of Retrograde Ejaculation: A Narrative Review

Diagnostics
Retrograde ejaculation (RE) is a condition where the forward expulsion of seminal fluid is impaired, leading to infertility and psychological distress in affected individuals.
Charalampos Konstantinidis, Athanasios Zachariou, Evangelini Evgeni, Selahittin Çayan, Luca Boeri, Ashok Agarwal   +5 more
doaj   +1 more source

Shock Wave Lithotripsy for Uric Acid Stones

Asian Journal of Surgery, 2006
To report our experience of extracorporeal shock wave lithotripsy (SWL) for patients with uric acid stones. Methods: From December 1987 to December 2003, a total of 443 patients with uric acid stones in the kidney or ureter accepted SWL using ultrasound ...
Xi-Zhao Sun, Zhi-Wei Zhang
doaj   +1 more source