Results 31 to 40 of about 18,738 (216)

Diagnostic accuracy of cytology and urine methylation test in patients with non-muscle invasive bladder cancer: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundMultiple clinical studies have demonstrated the numerous advantages of urine methylation test over cytology for monitoring patients with non-muscle invasive bladder cancer (NMIBC) following surgery.
Zhuoyue Yao, Tao Wang, Jingpeng Liu, Zhongbao Zhou, Yong Zhang   +4 more
doaj   +1 more source

Which urine marker test provides more diagnostic value in conjunction with standard cytology- ImmunoCyt/uCyt+ or Cytokeratin 20 expression

Diagnostic Pathology, 2009
Background Because of the poor sensitivity of urinary cytological findings for the diagnosis of especially low grade urinary bladder carcinoma, new molecular diagnostic methods have been proposed.
Soyuer Serdar, Tokat Fatma, Sofikerim Mustafa, Soyuer Isin, Ozturk Figen   +4 more
doaj   +1 more source

Urine Cytology Discrepancies [PDF]

American Journal of Clinical Pathology, 2007
Although urine cytology is used for the early detection and surveillance of urothelial carcinoma, there has been little study of the frequency, causes, and outcomes of cytologic-histologic discrepancies. We obtained histologic follow-up in 361 (6.2%) of 5,785 voided, 124 (19.5%) of 636 lower tract instrumented, and 23 (33%) of 69 upper tract urinary ...
Stephen S, Raab, Dana Marie, Grzybicki, Colleen M, Vrbin, Kim R, Geisinger   +3 more
openaire   +2 more sources

Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature

Advanced Science, EarlyView.
A deep learning model analyzes cfRNA profiles extracted from the blood of OVCA patients. This innovative approach distinguishes OVCA from healthy controls with high accuracy. Crucially, it reliably predicts patient response to chemotherapy (sensitive versus resistant subgroups).
Qinhao Guo, Yangyang Zhang, Yongcheng Jin, Siwei Deng, Yongqi Chen, Zheng Feng, Hao Wen, Liu Wang, Yilin Li, Fanghong Ou, Yong Shen, Haiming Li, Tianyao Zhou, Xingzhu Ju, Xiaohua Wu   +14 more
wiley   +1 more source

The Paris System – A new insight into reporting urine cytology

Journal of Pathology of Nepal, 2016
Urine cytology helps in the diagnosis of urothelial malignancies. There were no universally accepted reporting system despite several systems were suggested in the past.
A Ghosh
doaj   +1 more source

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Acu‐URO17 is a highly sensitive and specific bladder cancer biomarker

BJUI Compass
Objective This study evaluates the efficacy of Acu‐URO17, a highly sensitive and specific immunocytochemistry (ICC) test targeting Keratin 17, in comparison to urine cytology and UroVysion™ fluorescence in situ hybridization (FISH) for detecting bladder ...
Liwu Guo, Alexandra Cid, John Cucci, Brian Kunkel, Lisa Defeis, Michael Matthews   +5 more
doaj   +1 more source

Fibromyxoid Nephrogenic Adenoma Mimicking Renal Cell Carcinoma: A Diagnostic Pitfall in Fine‐Needle Aspiration Cytology

Diagnostic Cytopathology, EarlyView.
ABSTRACT Nephrogenic adenoma (NA) is a benign lesion of the genitourinary tract that may mimic malignancy both clinically and histologically. The fibromyxoid variant (FMNA), characterized by spindled cells in myxoid stroma, presents additional diagnostic challenges due to its rarity and overlapping features with renal cell carcinoma (RCC).
Jodi Gedallovich, Adebola Adeniyi, Ankur R. Sangoi, Xiaohua Qian, Kelly Ernst   +4 more
wiley   +1 more source

Clinical utility of photodynamic diagnosis with 5-aminolevulinic acid hydrochloride for detecting carcinoma in situ independent of urine cytology classification

Photodiagnosis and Photodynamic Therapy
Background: Urine cytology is a simple method used for diagnosing and monitoring bladder cancer. Although it offers very high specificity, its sensitivity for detecting low-grade urothelial carcinoma is limited.
Shinkuro Yamamoto, Hideo Fukuhara, Ryu Shigehisa, Takeshi Hara, Yasuhiko Shibanaka, Keiji Inoue   +5 more
doaj   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source