Results 61 to 70 of about 615 (116)

Urinary comprehensive genomic profiling predicts urothelial carcinoma recurrence and identifies responders to intravesical therapy

open access: yesMolecular Oncology, Volume 18, Issue 2, Page 291-304, February 2024.
This study used genomic profiling to detect mutations associated with urothelial carcinoma in patient urine samples collected before and after intravesical therapy. Genomic profiles informed an algorithmic assessment of minimal residual disease, which accurately predicted recurrence risk after surgery and quantified molecular response to therapy. These
Goran Rac   +14 more
wiley   +1 more source

Genomic analyses of an Escherichia coli and Klebsiella pneumoniae urinary tract co‐infection using long‐read nanopore sequencing

open access: yesMicrobiologyOpen, Volume 13, Issue 1, February 2024.
Two bacterial strains were recovered from the same catheter specimen of urine sample. The Escherichia coli strain encoded 11 resistance genes on a plasmid, including the ESBL gene, blaCTX‐M‐15. The Klebsiella pneumoniae strain encoded an additional 5 resistance genes on a plasmid, including 2 copies of blaCTX‐M‐15. Resistance genes were flanked between
Stephen Mark Edward Fordham   +3 more
wiley   +1 more source

Genomic Survey of E. coli From the Bladders of Women With and Without Lower Urinary Tract Symptoms

open access: yesFrontiers in Microbiology, 2020
Urinary tract infections (UTIs) are one of the most common human bacterial infections. While UTIs are commonly associated with colonization by Escherichia coli, members of this species also have been found within the bladder of individuals with no lower ...
Andrea Garretto   +42 more
doaj   +1 more source

Cluster information for induced prophages.

open access: yes, 2023
Due to its frequent association with urinary tract infections (UTIs), Escherichia coli is the best characterized constituent of the urinary microbiota (urobiome). However, uropathogenic E. coli is just one member of the urobiome. In addition to bacterial
Taylor Miller-Ensminger (8962898)   +6 more
core   +1 more source

PCR primers used to identify induced prophages.

open access: yes, 2023
Due to its frequent association with urinary tract infections (UTIs), Escherichia coli is the best characterized constituent of the urinary microbiota (urobiome). However, uropathogenic E. coli is just one member of the urobiome. In addition to bacterial
Taylor Miller-Ensminger (8962898)   +6 more
core   +1 more source

An expanded urine culturing workflow to cultivate and characterize diverse urobiome isolates

open access: yes
Despite increased recognition of the diverse resident microbiome of the urinary tract (i.e., the urobiome) in postmenopausal women, the roles and functions of these microbes remain largely unknown.
Thomas Hackl   +14 more
core   +1 more source

Emerging Role of Microbiome in the Prevention of Urinary Tract Infections in Children

open access: yes, 2022
The microbiome of the urinary tract plays a significant role in maintaining health through the impact on bladder homeostasis. Urobiome is of great importance in maintaining the urothelial integrity and preventing urinary tract infection (UTI), as well as
Danuta Zwolińska, Anna Kawalec
core   +1 more source

Urogenital microbiota-driven virulence factor genes associated with recurrent urinary tract infection

open access: yesFrontiers in Microbiology
Urinary tract infections (UTIs) are a common health issue affecting individuals worldwide. Recurrent urinary tract infections (rUTI) pose a significant clinical challenge, with limited understanding of the underlying mechanisms.
Lei Jiang   +6 more
doaj   +1 more source

DataSheet_1_The Urobiomes of Adult Women With Various Lower Urinary Tract Symptoms Status Differ: A Re-Analysis.docx

open access: yes, 2022
The discovery of the urinary microbiome (urobiome) has created opportunities for urinary health researchers who study a wide variety of human health conditions.
Linda Brubaker (651275)   +4 more
core   +1 more source

Characterization of the Urobiome in Danish Children

open access: yes
The urinary tract has long been considered sterile in healthy individuals, but recent advances in culture-independent methods such as 16S rRNA sequencing have revealed a diverse and dynamic urinary microbiome (urobiome).
Kock, Nicolai Claes   +8 more
core   +1 more source

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