Results 31 to 40 of about 17,246 (259)

Can Machine Learning Reduce Unnecessary Surgeries? A Retrospective Analysis Using Threshold Optimization to Prevent Negative Appendectomies in Adults

Annals of Gastroenterological Surgery, EarlyView.
Threshold‐optimized machine learning models using routine clinical and laboratory data in 623 adults undergoing appendectomy. Logistic regression (AUC = 0.765) and random forest (AUC = 0.785) were the best‐performing models for appendicitis detection and complicated appendicitis prediction, respectively.
Ivan Males, Marko Kumric, Zvonimir Boban, Josip Vrdoljak, Dario Pecenkovic, Matej Ivanda, Marko Grahovac, Zenon Pogorelic, Josko Bozic   +8 more
wiley   +1 more source

Comprehensive molecular profiling of FH-deficient renal cell carcinoma identifies molecular subtypes and potential therapeutic targets

Nature Communications
Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare yet highly lethal kidney cancer. To deepen our understanding of FH-deficient RCC, we conduct a comprehensive integrated genomic study.
Xingming Zhang, Junjie Zhao, Xiaoxue Yin, Jiayu Liang, Yongquan Wang, Linmao Zheng, Ping Tan, Yifei Lin, Nanwei Xu, Sha Zhu, Junru Chen, Jinge Zhao, Xu Hu, Xiuyi Pan, Ling Nie, Mengni Zhang, Yuntian Chen, Yaowen Zhang, Haoyang Liu, Jindong Dai, Zhipeng Wang, Haolin Liu, Yuchao Ni, Niels J. Rupp, Holger Moch, Xinan Sheng, Kan Gong, Xiaodong Liu, Zhibin Chen, Zhengyu He, Yaodong Wang, Lijing Xu, Mingsheng Liu, Hongqing Zhou, Bo Tang, Rui Huang, Qiang Wei, Xiang Li, Jiyan Liu, Jin Yao, Banghua Liao, Zhenhua Liu, Pengfei Shen, Ni Chen, Hao Zeng, Guangxi Sun   +45 more
doaj   +1 more source

Dielectric Elastomer Actuators as Safe and Effective Tools for Mechanostimulation of Human Cells

Advanced Intelligent Systems, EarlyView.
Replicating physiological forces is crucial for realistic cell models. Dielectric elastomer actuators (DEAs) offer a soft alternative, though their high voltages raised toxicity concerns. We demonstrate that DEA stimulation causes no cell damage, cell death or cell‐cycle disruption, while activating mechanosensitive responses.
Simon Holzer, Chaimae Bahou, Noe Syfrig, Katia Monastyrskaya, Yoan Civet, Ali Hashemi Gheinani, Yves Perriard   +6 more
wiley   +1 more source

Interleukins in Urological Diseases

Discovery Medicine
Interleukins (ILs) are a group of cytokines that regulate immune responses and inflammation, playing important roles in the pathogenesis, diagnosis, and treatment of urological diseases. This review provides an analysis of the involvement of interleukins in bladder cancer, benign prostatic hyperplasia (BPH), renal cell carcinoma (RCC), urinary tract ...
Hakan, Akdere, Burak, Bilir, Hasan Can, Kuvan, Gokhan, Cevik   +3 more
openaire   +4 more sources

Prevalence and management status of urologic disease in geriatric hospitals in South Korea: A population-based analysis [PDF]

Investigative and Clinical Urology, 2017
Purpose: This study aimed to investigate the prevalence and management status of urologic disease in geriatric hospitals in Korea. Materials and Methods: We conducted population-based analyzed using cohort established by the National Health Insurance ...
Jungyo Suh, Khae Hawn Kim, Sang Heon Lee, Hyung Suk Kim, Young Ju Lee, Sang Rim Lee, Chang Wook Jeong   +6 more
doaj   +1 more source

Electrocardiographic and Skin Manifestations of Turner Syndrome: Association With Cardiovascular Disease

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Congenital heart disease (CHD) and dermatologic conditions such as lymphedema and acquired melanocytic nevi (AMN) are common in Turner Syndrome (TS). We hypothesized that abnormalities of cranial neural crest cell derivatives drive the skin and heart manifestations of TS. We conducted joint cardiac and skin examinations of volunteers at a 2023
Sarah Elsaim, Brett Vernier, Van Thi Thanh Truong, Riya T. Patel, Matthew Brown, Martin Chacon Portillo, Megan Rogge, David Rodriguez‐Buritica, Siddharth K. Prakash   +8 more
wiley   +1 more source

The Role of Inflammasomes in Mediating Urological Disease: A Short Literature Review

Journal of Inflammation Research, 2022
Sarah Shidid,1 Martin H Bluth,2 Tamar A Smith-Norowitz1 1Department of Pediatrics, Division of Infectious Diseases, State University of New York Downstate Medical Center, New York, NY, 11203, USA; 2Department of Pathology, Maimonides Medical Center, New ...
Shidid S, Bluth MH, Smith-Norowitz TA
doaj  

Multidrug resistance and risk factors associated with community-acquired urinary tract infections caused by Escherichia coli in Venezuela

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction: The treatment of urinary tract infections has become more challenging due to the increasing frequency of multidrug-resistant Escherichia coli in human populations. Objective: To characterize multidrug-resistant E.
Militza Guzmán, Elsa Salazar, Vicmaris Cordero, Ana Castro, Andreína Villanueva, Hectorina Rodulfo, Marcos De Donato   +6 more
doaj   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

AI-assisted diagnosis of renal cell carcinoma: educational needs and cognitive assessment based on the WHO classification 2022

BMC Medical Education
This study explored medical students’ perceptions, educational needs, and cognitive biases toward Artificial Intelligence-assisted (AI-assisted) renal cell carcinoma (RCC) diagnosis, using the World Health Organization (WHO) 2022 classification.
Yuxi He, Xiaoxue Yin, Xu Shi, Qian Wang, Xingming Zhang   +4 more
doaj   +1 more source