Results 161 to 170 of about 379,515 (350)

Crucial Contribution of BACH1 to Bladder Cancer Progression via Upregulating Epithelial‐Mesenchymal Transition Pathway

Cancer Science, EarlyView.
BACH1 is associated with poor prognosis in BC patients and plays a critical role in promoting tumor progression and metastasis. Furthermore, we elucidated the mechanism by which BACH1 facilitates tumor progression and metastasis, primarily through activation of the EMT pathway. These findings suggest that BACH1 may serve as a novel prognostic biomarker
Tomoya Hatayama, Kenshiro Takemoto, Kohei Kobatake, Kento Miura, Liyanage P. Perera, Ryoken Yamanaka, Kazuma Yukihiro, Hiroyuki Shikuma, Kyosuke Iwane, Ryo Tasaka, Yuki Kohada, Miki Naito, Shunsuke Miyamoto, Yohei Sekino, Hiroyuki Kitano, Keisuke Goto, Akihiro Goriki, Keisuke Hieda, Osamu Kaminuma, Nobuyuki Hinata   +19 more
wiley   +1 more source

Longitudinal Impact of Urinary Diversion on Health‐Related Quality of Life After Radical Cystectomy: A Multicenter Study in Japan

Cancer Science, EarlyView.
This multicenter prospective study examined the impact of urinary diversion on HRQOL among bladder cancer patients who underwent radical cystectomy. Evaluation using the BCI clarified changes in HRQOL related to urinary, bowel, and sexual domains before surgery and at 3, 6, and 12 months postoperatively.
Shuhei Yamada, Miho Sato, Takahiro Osawa, Toru Harabayashi, Jun Miki, Takashi Kobayashi, Katsuyoshi Hashine, Atsunari Kawashima, Takashi Matsumoto, Takanori Mochizuki, Rikiya Taoka, Fumihiko Urabe, Shuichi Tatarano, Atsuro Sawada, Takahiro Kojima, Atsushi Takahashi, Akira Yokomizo, Shigetaka Suekane, Kohei Hashimoto, Yasuhiro Hashimoto, Junji Yatsuda, Ken Morita, Keita Kobayashi, Yohei Satake, Ataru Sazawa, Yoshiyuki Matsui, Yoichi M. Ito, Sayaka Shimizu, Shunichi Fukuhara, Hiroyuki Nishiyama, Hiroshi Kitamura, Nobuo Shinohara, on behalf of the Japanese Urological Oncology Group   +32 more
wiley   +1 more source

Validation of preoperative variables and stratification of patients to help predict benefit of cytoreductive nephrectomy in the targeted therapy ERA [PDF]

, 2017
Kim, Eric H, Manley, Brandon J, Potretzke, Aaron M, Strope, Seth A, Vetter, Joel M   +4 more
core   +2 more sources

Effectiveness and Safety of Radium‐223 for Bone‐Metastatic Castration‐Resistant Prostate Cancer: The KYUCOG‐1901 Study

Cancer Science, EarlyView.
The KYUCOG‐1901 prospective multicenter study evaluated radium‐223 in 93 Japanese patients with bone‐metastatic castration‐resistant prostate cancer. Ra‐223 was well tolerated, produced meaningful declines in ALP, and yielded a median overall survival of 23.0 months. Early initiation in patients with lower disease burden and integration with subsequent
Masaki Shiota, Shuichi Tatarano, Tomomi Kamba, Toshiyuki Kamoto, Tsukasa Igawa, Naoya Masumori, Hirotsugu Uemura, Kensuke Mitsunari, Takayuki Sumiyoshi, Hiroji Uemura, Katsuyoshi Higashijima, Shoji Tokunaga, Masatoshi Eto   +12 more
wiley   +1 more source

Mapping Dental Care for Children and Adolescents With Rare Diseases: A Brazilian Multicentre Study

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To describe the landscape of dental care provided by specialised centres for children and adolescents with rare diseases (RDs) in the state of Minas Gerais, southeastern Brazil. Methods A retrospective cross‐sectional study was conducted involving individuals aged 0–18 years with a confirmed diagnosis of a RD who received care at ...
Heloisa Vieira Prado, Rayssa Maria Soalheiro de Souza, Gabriella Guerra Freire Gabrich Fonseca, Kamila Rodrigues Junqueira Carvalho, Anna Vitória Mendes Viana Silva, Iasmin Fonseca Tolentino Mascarenhas, Beatriz Rezende Bergo, Hanna Larissa Barbosa Soares, Bárbara Mendes de Jesus, Layanne Ribeiro Ferreira e Sobral, Kélisson Duarte Reis, Késia Lara dos Santos Marques, Fabiana Sodré de Oliveira, Daniella Reis Barbosa Martelli, José Alcides Almeida de Arruda, Benjamin P. J. Fournier, Denise Vieira Travassos, Soraia Macari, Célia Regina Moreira Lanza, Ana Cristina Borges‐Oliveira, Hercílio Martelli‐Júnior, Tarcília Aparecida Silva   +21 more
wiley   +1 more source

Prevalence and Spectrum of Congenital Heart Disease in Individuals With Distal Chromosome 22q11.22–23 Deletions

Clinical Genetics, EarlyView.
The frequency and severity of congenital heart disease vary extensively in individuals with 22q11.22–23 distal deletions. Reduced gene dosage particularly within the low copy repeat (LCR22) D–E region including MAPK1 and HIC2 conveys risk for these defects.
Tanner J. Nelson, Daniel E. McGinn, T. Blaine Crowley, Lydia Rockart, Audrey Green, Victoria Giunta, Oanh Tran, Daniella Miller, Jeroen Breckpot, Ann Swillen, M. Cristina Digilio, Marta Unolt, Carolina Putotto, Federica Pulvirenti, Bruno Marino, Beverly S. Emanuel, Elaine H. Zackai, Zhengdong D. Zhang, Elizabeth Goldmuntz, Erik Boot, Anne S. Bassett, Bernice E. Morrow, Donna M. McDonald‐McGinn   +22 more
wiley   +1 more source

Molecular profile of atypical Leydig cell tumours

Histopathology, EarlyView.
Copy number variations by themselves are not sufficient to discriminate between benign and potential malignant Leydig cell tumours (LCTs). Genomic instability was only detected in malignant and atypical cases, and not in any benign tumours. Currently, the presence of metastasis remains the only malignant criterion for LCTs.
Muhammad F.K. Choudhry, Diogo Caires, Yaser Gamallat, Asli Yilmaz, Fadi Brimo, Bob Argiropoulos, Tarek A. Bismar   +6 more
wiley   +1 more source

Interobserver Discrepancy Using The 1998 World Health Organization/International Society Of Urologic Pathology Classification Of Urothelial Neoplasms: Practical Choices For Patient Care

, 2002
William M. Murphy, Kimiko Takezawa, NICHOLAS A. MARUNIAK   +2 more
openalex   +1 more source

Correlation of unfavourable and favourable histology at radical prostatectomy with Decipher scores and freedom from biochemical recurrence

Histopathology, EarlyView.
A recent study proposed a system of unfavourable and favourable histology categories to risk‐stratify prostate cancer patients. In a study of radical prostatectomy cases which had Decipher molecular classifier testing, unfavourable histology was associated with higher Decipher scores, increased biochemical recurrence (BCR) risk and improved BCR ...
Nancy Y Greenland, Janet E Cowan, Chien‐Kuang Cornelia Ding, Deepika Sirohi, Matthew R Cooperberg, Peter R Carroll, Jeffry P Simko, Bradley A Stohr, Li Zhang, Emily Chan   +9 more
wiley   +1 more source

The expression, regulation, and function of human endogenous retroviruses in genitourinary cancers. [PDF]

Cell Death Discov
Ma W, Ji C, Abudushataer A, Liu N, Xu T, Zhao K, Qian Y, Tuerxun P, Jiang X, Xiong Z, Wang M, Jia R, Xu Z, Li Y, Ge YZ.   +14 more
europepmc   +1 more source