p16 Overexpression and Human Papillomavirus Positivity in More Than 1000 Penile Cancers
ABSTRACT Penile cancer is a severe disease, and a large proportion is related to high‐risk (hr) human papillomavirus (HPV). P16 is used as an immunohistochemical marker of HPV in clinical diagnostics. Population‐based data on the prevalence of p16 in penile cancer is scarce.
Marianne Gardar Stærk +12 more
wiley +1 more source
Patient perspectives on single-port versus multi-port robotic-assisted urologic oncology procedures: a survey-based analysis. [PDF]
Nalluri R +3 more
europepmc +1 more source
Abstract Background Pre‐hospital emergency care is a critical component of emergency medical services (EMS), yet large‐scale epidemiological evidence from the main urban area of Chongqing remains limited. This study aimed to characterize the epidemiological profile and pre‐hospital outcomes of emergency patients in Chongqing from 2024 to 2025 and to ...
Liujiang Ran, Jun Si, Yanyan Liu
wiley +1 more source
A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia
Abstract The cellular composition and disease susceptibilities of the distinct zones of the human prostate remain incompletely understood. Benign prostatic hyperplasia (BPH) is a common condition that causes widespread morbidity and is nearly exclusively localized to the transition zone (TZ).
Rulin Wang +20 more
wiley +1 more source
Giant sacrococcygeal chordoma presenting with isolated urinary symptoms: A case report. [PDF]
Sacal JC, Torun AAS.
europepmc +1 more source
Chronic Scrotal Content Pain: A Practical Guide to Diagnosis and Management
ABSTRACT Chronic scrotal content pain (CSCP) is a common but often poorly understood condition that presents a significant diagnostic and therapeutic challenge. The broad differential diagnosis and frequent absence of an identifiable cause can lead to repeated investigations, delayed treatment and unnecessary surgery.
Mahin Chowdhury +6 more
wiley +1 more source
Migration status and urologic health inequities: a scoping review. [PDF]
Goodarzi K +4 more
europepmc +1 more source
Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin +10 more
wiley +1 more source
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li +21 more
wiley +1 more source
The role of lipid-lowering drugs in urologic and male reproductive cancers: a Mendelian randomization study. [PDF]
Lin YT +6 more
europepmc +1 more source

