Results 171 to 180 of about 113,524 (243)

p16 Overexpression and Human Papillomavirus Positivity in More Than 1000 Penile Cancers

open access: yesInternational Journal of Cancer, Volume 159, Issue 12, Page 3029-3037, 15 December 2026.
ABSTRACT Penile cancer is a severe disease, and a large proportion is related to high‐risk (hr) human papillomavirus (HPV). P16 is used as an immunohistochemical marker of HPV in clinical diagnostics. Population‐based data on the prevalence of p16 in penile cancer is scarce.
Marianne Gardar Stærk   +12 more
wiley   +1 more source

Epidemiological characteristics and pre‐hospital treatment outcomes of pre‐hospital emergency patients in the main urban area of Chongqing, 2024–2025

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 6, December 2026.
Abstract Background Pre‐hospital emergency care is a critical component of emergency medical services (EMS), yet large‐scale epidemiological evidence from the main urban area of Chongqing remains limited. This study aimed to characterize the epidemiological profile and pre‐hospital outcomes of emergency patients in Chongqing from 2024 to 2025 and to ...
Liujiang Ran, Jun Si, Yanyan Liu
wiley   +1 more source

A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia

open access: yesThe Journal of Pathology, Volume 270, Issue 4, Page 481-496, December 2026.
Abstract The cellular composition and disease susceptibilities of the distinct zones of the human prostate remain incompletely understood. Benign prostatic hyperplasia (BPH) is a common condition that causes widespread morbidity and is nearly exclusively localized to the transition zone (TZ).
Rulin Wang   +20 more
wiley   +1 more source

Chronic Scrotal Content Pain: A Practical Guide to Diagnosis and Management

open access: yesTrends in Urology &Men's Health, Volume 17, Issue 6, December 2026.
ABSTRACT Chronic scrotal content pain (CSCP) is a common but often poorly understood condition that presents a significant diagnostic and therapeutic challenge. The broad differential diagnosis and frequent absence of an identifiable cause can lead to repeated investigations, delayed treatment and unnecessary surgery.
Mahin Chowdhury   +6 more
wiley   +1 more source

Migration status and urologic health inequities: a scoping review. [PDF]

open access: yesCurr Opin Urol
Goodarzi K   +4 more
europepmc   +1 more source

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

open access: yesInternational Journal of Cancer, Volume 159, Issue 10, Page 2585-2594, 15 November 2026.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin   +10 more
wiley   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li   +21 more
wiley   +1 more source

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