Results 181 to 190 of about 19,955 (310)

Comprehensive molecular profiling of urologic tumors presented in a molecular tumor board: insights from a real-world precision oncology cohort. [PDF]

open access: yesFront Oncol
Glienke M   +15 more
europepmc   +1 more source

Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5*6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 942-952, April 2026.
Pharmacogenomic research has historically focused on individuals of European ancestry, leading to the underrepresentation of genetic variants common in non‐European populations. This bias is exemplified by CYP3A5*6, a functionally consequential variant common in individuals of African ancestry (MAF: 11–19%) but virtually absent in Europeans (MAF: 0.15%)
Amar D. Levens   +10 more
wiley   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi   +5 more
wiley   +1 more source

Diagnostic Value of Rapid On‐Site Evaluation Combined With Prostate Biopsy in Prostate Cancer

open access: yesThe Prostate, Volume 86, Issue 5, Page 542-549, April 2026.
ABSTRACT Objective To investigate the application value of Rapid On‐Site Evaluation (ROSE) in prostate biopsy. Methods All consecutive subjects who attended our clinic to underwent magnetic resonance imaging (MRI)‐ultrasound fusion biopsy due to highly suspicious findings on MRI for prostate cancer (PCa) and met the inclusion criteria were enrolled ...
Hong Ma   +5 more
wiley   +1 more source

Urine‐Based Bladder Cancer Diagnostics: A Local Evaluation of Cxbladder and Review of the ANZ Landscape

open access: yesTrends in Urology &Men's Health, Volume 17, Issue 2, April 2026.
ABSTRACT The high demand for cystoscopies performed for bladder cancer diagnosis or surveillance imposes a significant burden on regional centres with limited capacity. Cxbladder is a urinary biomarker test that estimates the likelihood of bladder cancer.
Claris Oh   +4 more
wiley   +1 more source

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