Results 191 to 200 of about 380,997 (339)

Loss of METTL3 m6A methyltransferase results in short‐term progression and poor treatment outcome of bladder cancer patients

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 763-774, 1 February 2026.
What's new? Bladder cancer exhibits a highly heterogeneous molecular landscape and treatment response. The dysregulation of RNA modifications such as m6A has been involved in cancer initiation and progression. This study comprehensively analyzed the expression of the main catalytic component of the m6A methylation machinery in bladder tumors across one
Katerina‐Marina Pilala   +10 more
wiley   +1 more source

Assessing Quality and Adherence to PI‐RADSv2.1 Minimum Technical Standards of Prostate MRI in NRG‐GU005

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 464-474, February 2026.
ABSTRACT Background Multi‐parametric MRI (mpMRI) datasets often vary between sites due to differences in acquisition protocols. Purpose Evaluate adherence of multi‐site mpMRI dataset to minimum technical standards (MTS) of PI‐RADSv2.1. Study Type Prospective.
Stephanie Alley   +20 more
wiley   +1 more source

Accelerating 2D Kidney Magnetic Resonance Fingerprinting Using Deep Learning Based Tissue Quantification

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 525-535, February 2026.
ABSTRACT Background Magnetic Resonance Fingerprinting (MRF) is a technique that can provide rapid quantification of multiple tissue properties. Deep learning may potentially contribute to an accelerated acquisition of MRF. Purpose (1) To develop a deep learning method to accelerate the acquisition for kidney MRF; (2) to evaluate its performance in ...
Zhiqing Yin   +8 more
wiley   +1 more source

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

open access: yesMedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin   +12 more
wiley   +1 more source

Estrogen regulation in the prostate underlies racial disparity in men with benign prostatic hyperplasia

open access: yesThe Journal of Pathology, Volume 268, Issue 2, Page 176-187, February 2026.
Abstract Lower urinary tract symptoms (LUTS), associated with benign prostatic hyperplasia (BPH), are an aging‐related disease, with more than 210 million cases worldwide. Estrogen exposure and estrogen regulation have been implicated in a variety of disease processes, with estrogen receptor (ER)‐α pathways associated with disease progression and ERβ ...
Teresa T Liu   +9 more
wiley   +1 more source

Papillary renal cell carcinoma with high‐ABCC2 shows an immune‐evasive profile associated with favorable response to immunotherapy

open access: yesThe Journal of Pathology, Volume 268, Issue 2, Page 188-199, February 2026.
Abstract The use of immune checkpoint inhibitors is a promising therapeutic strategy for metastatic papillary renal cell carcinoma (PRCC); however, predictive biomarkers remain limited. PRCCs with high ABCC2 expression represent an aggressive subset frequently associated with metastasis.
Vincent Francis Castillo   +8 more
wiley   +1 more source

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