Results 161 to 170 of about 275,962 (319)

Scope and Limitations of the Use of Methanesulfonic Acid (MSA) as a Green Acid for Global Deprotection in Solid‐Phase Peptide Synthesis

open access: yesChemSusChem, EarlyView.
TFA is the only acid used for the cleavage of peptides from the resin. However, this acid belongs to the PFAS family, which is anticipated to face usage restrictions. Herein, the use of MSA, which is a “Natural Green Acid” is proposed to substitute TFA for the global deprotection and cleavage in SPPS.
Giovanni Vivenzio   +5 more
wiley   +1 more source

The Impact of Triptorelin on Hormone Levels in Human and Its Metabolite Confirmation Using Liquid Chromatography–Ion Trap/Time‐of‐Flight Mass Spectrometry (LC/MS‐IT‐TOF) and Liquid Chromatography–Orbitrap (LC‐Orbitrap) for Doping Control Analysis

open access: yesDrug Testing and Analysis, EarlyView.
Triptorelin (5–10) confirmation using LC/MS‐IT‐TOF and LC‐Orbitrap can be used as evidence of triptorelin abuse in doping control. ABSTRACT Triptorelin, a synthetic gonadotrophin‐releasing hormone (GnRH), is mainly used in the clinical treatment of prostate cancer.
Navaporn Saardpun   +6 more
wiley   +1 more source

Isolated rupture of the corpus spongiosum with urethral injury diagnosed by pre‐surgical MRI

open access: yesIJU Case Reports, Volume 6, Issue 1, Page 70-72, January 2023., 2023
Introduction Penile fracture is typically defined as the rupture of the corpus cavernosum. Case presentation A 61‐year‐old man presented with swelling, pain, and bruising of his penis, along with gross hematuria. He reported that he sustained this injury while having sex with his wife.
Shuhei Yokoyama   +8 more
wiley   +1 more source

Gynecologic and Obstetric Urology

open access: bronze, 1948
NULL AUTHOR_ID
openalex   +1 more source

Poor communication impairs optimal care of patients with heart failure and erectile dysfunction

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Heart failure (HF) and erectile dysfunction (ED) share numerous risk factors and pathogenetic mechanisms, resulting in a high prevalence of ED among male patients with HF. This questionnaire‐based study aimed to better understand the patient's journey from a patient perspective and that of healthcare professionals (HCPs) regarding ...
Lea Leist, Lenka Hausmann, Carla Pohlink
wiley   +1 more source

Dual‐Responsive Multi‐Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury

open access: yesExploration, EarlyView.
Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby ...
Guibin Gao   +12 more
wiley   +1 more source

Sunitinib in metastatic renal cell carcinoma: clinical outcomes across risk groups in a Turkish Oncology Group Kidney Cancer Consortium

open access: yes
Cancer Communications, EarlyView.
Hatice Bolek   +17 more
wiley   +1 more source

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